Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 8/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.51 |
| ▸ | KDR | P35968 | 3/20 | 0.51 |
| ▸ | ARAF | P10398 | 1/20 | 0.51 |
| ▸ | BRAF | P15056 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 2/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28963967 | 1.00 | RAF1 (0.51) | RAF1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30142976 | 0.92 | RAF1 (0.55) | RAF1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28943458 | 0.92 | RAF1 (0.55) | RAF1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28943449 | 0.87 | RAF1 (0.70) | RAF1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28963973 | 0.87 | RAF1 (0.70) | RAF1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28943467 | 0.83 | RAF1 (0.68) | RAF1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28943481 | 0.82 | RAF1 (0.68) | RAF1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28943521 | 0.81 | RAF1 (0.67) | RAF1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28943464 | 0.80 | RAF1 (0.71) | RAF1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30142965 | 0.76 | SMN1; SMN2 (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848506-B | Biphenyl urea compound and pharmaceutical composition, preparation method and application thereof | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |