Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | BCL2L2 | Q92843 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 4/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LDHB | P07195 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30143439 | 0.85 | ALB (0.38) | BCL2BCL2L1MCL1BCL2L2ALB | |
| SCHEMBL30143357 | 0.85 | MCL1 (0.54) | BCL2BCL2L1MCL1BCL2L2ALB | |
| SCHEMBL30143373 | 0.74 | MCL1 (0.77) | BCL2BCL2L1MCL1BCL2L2ALB | |
| SCHEMBL26996418 | 0.70 | BCL2L1 (0.60) | BCL2BCL2L1MCL1BCL2L2ALB | |
| SCHEMBL20314890 | 0.65 | LMNA (0.50) | ALBKDM4ELDHAALDH1A1LMNA | |
| SCHEMBL20314851 | 0.65 | LMNA (0.50) | ALBKDM4ELDHAALDH1A1LMNA | |
| SCHEMBL30143412 | 0.64 | LMNA (0.50) | BCL2BCL2L1MCL1BCL2L2ALB | |
| SCHEMBL3283300 | 0.63 | CA1 (0.52) | GABRA1GABRB1MEN1USP2ALDH1A1 | |
| SCHEMBL22880752 | 0.62 | CA1 (0.33) | GABRA1GABRB1ESR1CA1CA2 | |
| SCHEMBL1760529 | 0.61 | CA1 (0.70) | GABRA1GABRB1MEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536496-A | Synthesis method of selective dehydroxy apogossypol | 江苏度未生物工程科技有限公司 | 2022-12-30 | — | — | CN | disclosed |