Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.66 |
| ▸ | AR | P10275 | 3/20 | 0.57 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.50 |
| ▸ | BTK | Q06187 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | PLK4 | O00444 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23860209 | 1.00 | CRBN (0.66) | CRBNARDDB1BTKALDH1A1 | |
| SCHEMBL20046266 | 0.94 | CRBN (0.74) | CRBNARDDB1ALDH1A1CHRM2 | |
| SCHEMBL29426684 | 0.94 | CRBN (0.74) | CRBNARDDB1ALDH1A1CHRM2 | |
| SCHEMBL31628425 | 0.91 | CRBN (0.64) | CRBNARDDB1BTKALDH1A1 | |
| SCHEMBL25329541 | 0.91 | CRBN (0.66) | CRBNARDDB1BTKALDH1A1 | |
| SCHEMBL26969608 | 0.91 | CRBN (0.66) | CRBNARDDB1BTKALDH1A1 | |
| SCHEMBL31447732 | 0.89 | CRBN (0.80) | CRBNARDDB1BTKALDH1A1 | |
| SCHEMBL24421652 | 0.89 | CRBN (0.69) | CRBNARDDB1BTKALDH1A1 | |
| SCHEMBL26969669 | 0.89 | CRBN (0.69) | CRBNARDDB1BTKALDH1A1 | |
| SCHEMBL30160860 | 0.89 | CRBN (0.74) | CRBNARDDB1BTKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025124516-A1 | COMPOUND HAVING AKT KINASE-DEGRADING ACTIVITY, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 南京正大天晴制药有限公司 | 2025-06-19 | — | — | WO | disclosed |
| CN-115697990-B | Indazole-based compounds and related methods of use | 阿维纳斯企业公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-115697990-A | Indazole-based compounds and related methods of use | 阿维纳斯企业公司 | 2023-02-03 | — | — | CN | disclosed |
| EP-4121422-A1 | INDAZOLE BASED COMPOUNDS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |
| EP-4121167-A1 | SELECTIVE MODULATORS OF MUTANT LRRK2 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |