Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.66 |
| ▸ | AR | P10275 | 4/20 | 0.58 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.52 |
| ▸ | BTK | Q06187 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | PLK4 | O00444 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26969608 | 1.00 | CRBN (0.66) | CRBNARDDB1BTKALDH1A1 | |
| SCHEMBL31306523 | 0.93 | CRBN (0.66) | CRBNARDDB1BTKALDH1A1 | |
| SCHEMBL20317461 | 0.91 | CRBN (0.79) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL30144121 | 0.91 | CRBN (0.66) | CRBNARDDB1BTKALDH1A1 | |
| SCHEMBL23860209 | 0.91 | CRBN (0.66) | CRBNARDDB1BTKALDH1A1 | |
| SCHEMBL31447732 | 0.89 | CRBN (0.80) | CRBNARDDB1BTKALDH1A1 | |
| SCHEMBL24421652 | 0.89 | CRBN (0.69) | CRBNARDDB1BTKALDH1A1 | |
| SCHEMBL26969669 | 0.89 | CRBN (0.69) | CRBNARDDB1BTKALDH1A1 | |
| SCHEMBL30160860 | 0.89 | CRBN (0.74) | CRBNARDDB1BTKALDH1A1 | |
| SCHEMBL30692989 | 0.88 | CRBN (0.65) | CRBNARDDB1BTKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143482-A1 | 2-AMINOPYRIMIDINE COMPOUND OR SALT, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海辉启生物医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |