Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 18/20 | 0.44 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23860090 | 1.00 | LRRK2 (0.44) | LRRK2NMT1ACVR1 | |
| SCHEMBL23860100 | 0.80 | LRRK2 (0.37) | LRRK2 | |
| SCHEMBL16025597 | 0.78 | LRRK2 (0.47) | LRRK2NMT1 | |
| SCHEMBL23860256 | 0.77 | LRRK2 (0.72) | LRRK2 | |
| SCHEMBL16014230 | 0.77 | LRRK2 (0.57) | LRRK2 | |
| SCHEMBL16025532 | 0.75 | LRRK2 (0.47) | LRRK2 | |
| SCHEMBL16014153 | 0.75 | LRRK2 (0.47) | LRRK2 | |
| SCHEMBL16025794 | 0.75 | LRRK2 (0.45) | LRRK2 | |
| SCHEMBL23910154 | 0.74 | LRRK2 (0.39) | LRRK2 | |
| SCHEMBL16025904 | 0.73 | DGAT1 (0.37) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697990-B | Indazole-based compounds and related methods of use | 阿维纳斯企业公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-115697990-A | Indazole-based compounds and related methods of use | 阿维纳斯企业公司 | 2023-02-03 | — | — | CN | disclosed |
| EP-4121422-A1 | INDAZOLE BASED COMPOUNDS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |