Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.67 |
| ▸ | DDB1 | Q16531 | 10/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23860106 | 1.00 | CRBN (0.67) | CRBNDDB1EGFRBRD9ALDH1A1 | |
| SCHEMBL31655708 | 0.95 | CRBN (0.63) | CRBNDDB1EGFRBRD9 | |
| SCHEMBL22291304 | 0.95 | CRBN (0.63) | CRBNDDB1EGFRBRD9 | |
| SCHEMBL23860197 | 0.94 | CRBN (0.70) | CRBNDDB1EGFRALDH1A1CHRM2 | |
| SCHEMBL22290148 | 0.92 | CRBN (0.64) | CRBNDDB1EGFRBRD9HPGDS | |
| SCHEMBL24207009 | 0.87 | CRBN (0.71) | CRBNDDB1EGFRBRD9ALDH1A1 | |
| SCHEMBL23860665 | 0.87 | CRBN (0.71) | CRBNDDB1EGFRBRD9ALDH1A1 | |
| SCHEMBL31297121 | 0.87 | CRBN (0.71) | CRBNDDB1EGFRBRD9ALDH1A1 | |
| SCHEMBL30619696 | 0.87 | CRBN (0.74) | CRBNDDB1EGFRBRD9ALDH1A1 | |
| SCHEMBL30183349 | 0.87 | CRBN (0.71) | CRBNDDB1EGFRBRD9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121422-A1 | INDAZOLE BASED COMPOUNDS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |