Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DTYMK | P23919 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | PPOX | P50336 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL580364 | 1.00 | DTYMK (0.42) | DTYMKSERPINE1AKR1B1AKR1C4AKR1C3 | |
| SCHEMBL586740 | 0.90 | DTYMK (0.48) | DTYMKALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL18936887 | 0.85 | APP (0.39) | SERPINE1AKR1B1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL3950613 | 0.83 | EGFR (0.55) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL27545640 | 0.83 | GAA (0.42) | SERPINE1ALDH1A1MAPTTDP1AR | |
| SCHEMBL580229 | 0.83 | PPARA (0.55) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL580270 | 0.82 | KDM4E (0.47) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL3996778 | 0.82 | PPARA (0.54) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL3996092 | 0.82 | PPARA (0.54) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL581497 | 0.82 | PPARA (0.40) | ALDH1A1MAPTTDP1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515573-A | Compositions and methods for treating reperfusion injury or bleeding following recanalization | GNT制药有限公司 | 2022-12-23 | — | — | CN | claimed |
| EP-4117648-A1 | COMPOSITIONS AND METHODS FOR TREATING REPERFUSION INJURY OR HEMORRHAGE AFTER RECANALIZATION THERAPY | GNT Pharma Co., Ltd (KR) | 2023-01-18 | — | — | EP | disclosed |
| CN-115515573-A | Compositions and methods for treating reperfusion injury or bleeding following recanalization | GNT制药有限公司 | 2022-12-23 | — | — | CN | disclosed |