Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.55 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 7/20 | 0.53 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RGS12 | O14924 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.52 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | LDHB | P07195 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium SCHEMBL29515374 | 0.99 | PPARA (0.54) | PPARASTING1EGFRNOX4ALDH1A1 | |
| SCHEMBL3996747 | 0.99 | PPARA (0.54) | PPARASTING1EGFRNOX4ALDH1A1 | |
| SCHEMBL3996778 | 0.99 | PPARA (0.54) | PPARASTING1EGFRNOX4ALDH1A1 | |
| SCHEMBL3996092 | 0.99 | PPARA (0.54) | PPARASTING1EGFRNOX4ALDH1A1 | |
| Sulfuric Acid SCHEMBL28638816 | 0.95 | PPARA (0.51) | PPARASTING1EGFRNOX4ALDH1A1 | |
| SCHEMBL499950 | 0.89 | PPARA (0.63) | PPARASTING1EGFRNOX4ALDH1A1 | |
| SCHEMBL30473063 | 0.89 | PPARA (0.63) | PPARASTING1EGFRNOX4ALDH1A1 | |
| SCHEMBL3955043 | 0.89 | PPARA (0.43) | PPARASTING1EGFRNOX4ALDH1A1 | |
| Lithium Ion SCHEMBL3996773 | 0.88 | PPARA (0.42) | PPARASTING1EGFRNOX4ALDH1A1 | |
| SCHEMBL3996087 | 0.88 | PPARA (0.42) | PPARASTING1EGFRNOX4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12576091-B2 | Preparation method of salfaprodil freeze-dried powder injection, and product and use thereof | GNT PHARMA CO., LTD. (KR) | 2026-03-17 | — | — | US | claimed |
| US-20260027076-A1 | COMPOSITIONS AND METHODS FOR TREATING REPERFUSION INJURY OR HEMORRHAGE AFTER RECANALIZATION THERAPY | GNT PHARMA CO LTD (KR) | 2026-01-29 | — | — | US | claimed |
| US-12433861-B2 | Compositions and methods for treating reperfusion injury or hemorrhage after recanalization therapy | GNT PHARMA CO., LTD. (KR) | 2025-10-07 | — | — | US | claimed |
| US-20230390231-A1 | COMPOSITIONS AND METHODS FOR TREATING REPERFUSION INJURY OR HEMORRHAGE AFTER RECANALIZATION THERAPY | GNT PHARMA CO., LTD. (KR) | 2023-12-07 | — | — | US | claimed |
| US-11826329-B2 | Compositions and methods for treating reperfusion injury or hemorrhage after recanalization therapy | GNT PHARMA CO., LTD. (KR) | 2023-11-28 | — | — | US | claimed |
| US-20230270757-A1 | PREPARATION METHOD OF SALFAPRODIL FREEZE-DRIED POWDER INJECTION, AND PRODUCT AND USE THEREOF | GNT PHARMA CO., LTD. (KR) | 2023-08-31 | — | — | US | claimed |
| EP-4190314-A1 | PREPARATION METHOD OF SALFAPRODIL FREEZE-DRIED POWDER INJECTION, AND PRODUCT AND USE THEREOF | GNT Pharma Co., Ltd (KR) | 2023-06-07 | — | — | EP | claimed |
| EP-4117648-A1 | COMPOSITIONS AND METHODS FOR TREATING REPERFUSION INJURY OR HEMORRHAGE AFTER RECANALIZATION THERAPY | GNT Pharma Co., Ltd (KR) | 2023-01-18 | — | — | EP | claimed |
| CN-115515573-A | Compositions and methods for treating reperfusion injury or bleeding following recanalization | GNT制药有限公司 | 2022-12-23 | — | — | CN | claimed |
| CN-108164431-B | 2-hydroxy-5- (2,3,5, 6-tetrafluoro-4-trifluoromethyl benzylamino) benzoic acid and preparation method thereof | 浙江普洛家园药业有限公司 | 2021-10-08 | — | — | CN | claimed |
| US-20070049565-A1 | Combination of cell necrosis inhibitor and lithium for treating neuronal death or neurological dysfunction | NEUROTECH PHARMACEUTICALS CO., LTD. (KR) | 2007-03-01 | — | — | US | claimed |
| WO-2006126846-A1 | PROCESS OF PREPARATION OF SUBSTITUTED TETRAFLUOROBENZYLANILINE COMPOUND AND ITS PHARMACEUTICALLY APPROVED SALTS | CHOONGWAE PHARMA CORPORATION (KR) | 2006-11-30 | — | — | WO | claimed |
| WO-2006126825-A1 | COMPOSITION COMPRISING TETRAFLUOROBENZYL DERIVATIVES OR SALTS OF THEREOF FOR INJECTION | CHOONGWAE PHARMA CORPORATION (KR) | 2006-11-30 | — | — | WO | claimed |
| US-20060235239-A1 | Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same | NEUROTECH CO., LTD. (KR) | 2006-10-19 | — | — | US | claimed |
| CN-1738627-A | Method for inhibiting necrosis induced by neurotrophic factor | NEUROTECH PHARMACEUTICALS CO L (KR) | 2006-02-22 | — | — | CN | claimed |
| CN-1668576-A | Tetrafluorobenzyl derivatives and pharmaceutical composition for treating and preventing acute and chronic neurodegenerative diseases of central nervous system containing the same | NEUROTECH CO LTD (KR) | 2005-09-14 | — | — | CN | claimed |
| US-6927303-B2 | Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same | NEUROTECH CO., LTD. (KR) | 2005-08-09 | — | — | US | claimed |
| EP-1551793-A1 | TETRAFLUOROBENZYL DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING ACUTE AND CHRONIC NEURODEGENERATIVE DISEASES IN CENTRAL NERVOUS SYSTEM CONTAINING THE SAME | Neurotech Co., Ltd. (KR) | 2005-07-13 | — | — | EP | claimed |
| US-20040209957-A1 | Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same | NEUROTECH PHARMACEUTICALS CO., LTD. (KR) | 2004-10-21 | — | — | US | claimed |
| WO-2004000786-A1 | TETRAFLUOROBENZYL DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING ACUTE AND CHRONIC NEURODEGENERATIVE DISEASES IN CENTRAL NERVOUS SYSTEM CONTAINING THE SAME | NEUROTECH CO., LTD. (KR) | 2003-12-31 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12433861-B2 | Compositions and methods for treating reperfusion injury or hemorrhage after recanalization therapy | PLAT, SERPINE1, SERPINC1 | PPARA 3027/4885STING1 2135/4885EGFR 100/4885 |
| US-11826329-B2 | Compositions and methods for treating reperfusion injury or hemorrhage after recanalization therapy | PLAT, SERPINE1, SERPINC1 | PPARA 3027/4885STING1 2135/4885EGFR 100/4885 |
| US-20230390231-A1 | COMPOSITIONS AND METHODS FOR TREATING REPERFUSION INJURY OR HEMORRHAGE AFTER RECANALIZATION THERAPY | PLAT, SERPINE1, SERPINC1 | PPARA 3027/4885STING1 2135/4885EGFR 100/4885 |
| US-20260027076-A1 | COMPOSITIONS AND METHODS FOR TREATING REPERFUSION INJURY OR HEMORRHAGE AFTER RECANALIZATION THERAPY | FGB, PLAT, CTSH | PPARA 348/4885STING1 3196/4885EGFR 169/4885 |
| US-20230270757-A1 | PREPARATION METHOD OF SALFAPRODIL FREEZE-DRIED POWDER INJECTION, AND PRODUCT AND USE THEREOF | PGF, SALL4, FIBP | PPARA 146/4885STING1 3632/4885EGFR 3902/4885 |
| US-12576091-B2 | Preparation method of salfaprodil freeze-dried powder injection, and product and use thereof | PGF, PGA5, PDE5A | PPARA 704/4885STING1 3602/4885EGFR 4233/4885 |
| US-20070049565-A1 | Combination of cell necrosis inhibitor and lithium for treating neuronal death or neurological dysfunction | BAD, MAP1LC3B, XIAP | PPARA 4072/4885STING1 3607/4885EGFR 2579/4885 |
| US-20060235239-A1 | Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same | HTT, BDNF, APP | PPARA 289/4885STING1 4579/4885EGFR 510/4885 |
| US-20040209957-A1 | Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same | HTT, BDNF, APP | PPARA 289/4885STING1 4579/4885EGFR 510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.