Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3014456 | 1.00 | AKR1B1 (0.42) | AKR1B1SMN1; SMN2KMT2ACYP3A4CYP2C9 | |
| SCHEMBL3021784 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AMEN1LMNAMAPT | |
| SCHEMBL3021788 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AMEN1LMNAMAPT | |
| SCHEMBL919045 | 0.79 | ABCB1 (0.40) | CYP2C9CYP2C19CYP2D6CYP1A2HPGD | |
| SCHEMBL919048 | 0.79 | ABCB1 (0.40) | CYP2C9CYP2C19CYP2D6CYP1A2HPGD | |
| SCHEMBL3019977 | 0.77 | HDAC3 (0.44) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL3019983 | 0.77 | HDAC3 (0.44) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL18191123 | 0.76 | MAPT (0.40) | SMN1; SMN2KMT2AMEN1HSD17B10MAPT | |
| SCHEMBL3014458 | 0.74 | AKR1B1 (0.41) | AKR1B1SMN1; SMN2KMT2ACYP3A4CYP2C9 | |
| SCHEMBL7637016 | 0.74 | AKR1B1 (0.55) | AKR1B1SMN1; SMN2KMT2ACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242055-B2 | Herbicidally and insecticidally active phenyl-substituted pyridazinones | BAYER CROPSCIENCE AG (DE) | 2012-08-14 | — | — | US | disclosed |
| US-20100184602-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184602-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | CYP4X1, PRDX1, PNPO | AKR1B1 208/4885SMN1; SMN2 3492/4885KMT2A 1579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.