SCHEMBL30144804

SCHEMBL30144804

Cc1ccc2c(c1)[C@@H](N)[C@H](C)C2

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.41
AADAT Q8N5Z0 2/20 0.38
TRPM5 Q9NZQ8 1/20 0.38
CHRNB2 P17787 1/20 0.34
CHRNA4 P43681 1/20 0.34
HTR2C P28335 3/20 0.34
HTR2A P28223 1/20 0.34
HTR2B P41595 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
HTR5A P47898 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2569128 1.00 ACHE (0.41) ACHEAADATTRPM5CHRNB2CHRNA4
SCHEMBL31453975 1.00 ACHE (0.41) ACHEAADATTRPM5CHRNB2CHRNA4
SCHEMBL30686750 1.00 ACHE (0.41) ACHEAADATTRPM5CHRNB2CHRNA4
SCHEMBL29103302 1.00 ACHE (0.41) ACHEAADATTRPM5CHRNB2CHRNA4
SCHEMBL1735274 1.00 ACHE (0.41) ACHEAADATTRPM5CHRNB2CHRNA4
SCHEMBL1734307 1.00 ACHE (0.41) ACHEAADATTRPM5CHRNB2CHRNA4
SCHEMBL29478339 1.00 ACHE (0.41) ACHEAADATTRPM5CHRNB2CHRNA4
SCHEMBL31186259 1.00 ACHE (0.41) ACHEAADATTRPM5CHRNB2CHRNA4
SCHEMBL2923220 1.00 ACHE (0.41) ACHEAADATTRPM5CHRNB2CHRNA4
SCHEMBL27115616 1.00 ACHE (0.41) ACHEAADATTRPM5CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108794339-B Preparation method of (1R, 2S) -2, 6-dimethyl-1-aminoindane 上海朴颐化学科技有限公司 2023-01-20 CN claimed
CN-119661374-A Method for preparing (1R, 2S) -2, 6-dimethyl-1-indene amine by using chiral amino acid resolving agent 中国科学院大连化学物理研究所 2025-03-21 CN disclosed
CN-118878424-A Synthesis method of indene fluorooxamide intermediate indene amine 安徽省化工研究院 2024-11-01 CN disclosed
CN-108794339-B Preparation method of (1R, 2S) -2, 6-dimethyl-1-aminoindane 上海朴颐化学科技有限公司 2023-01-20 CN disclosed