Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 6/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | AGXT | P21549 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7914167 | 1.00 | ABCB1 (0.59) | ABCB1NPC1RAB9AHTR1AADRA1D | |
| SCHEMBL16018989 | 0.87 | ABCB1 (0.68) | ABCB1NPC1RAB9AHTR1AADRA1D | |
| SCHEMBL1028222 | 0.85 | MAPT (0.53) | ABCB1NPC1RAB9AHTR1AADRA1D | |
| SCHEMBL29070964 | 0.85 | MAPT (0.47) | ABCB1NPC1RAB9AHTR1AADRA1D | |
| SCHEMBL2549427 | 0.85 | ABCB1 (0.60) | ABCB1NPC1RAB9AHTR1AMAOB | |
| SCHEMBL30568078 | 0.83 | NPC1 (0.50) | ABCB1NPC1RAB9AHTR1AADRA1D | |
| SCHEMBL22440512 | 0.83 | NPC1 (0.50) | ABCB1NPC1RAB9AHTR1AADRA1D | |
| SCHEMBL19140088 | 0.82 | MAPT (0.52) | NPC1RAB9AHTR1AADRA1DADRA1A | |
| SCHEMBL30568081 | 0.82 | NPC1 (0.49) | ABCB1NPC1RAB9AHTR1AADRA1D | |
| SCHEMBL22440506 | 0.82 | NPC1 (0.49) | ABCB1NPC1RAB9AHTR1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111247148-B | Wnt pathway modulators | 新加坡科技研究局 | 2022-12-20 | — | — | CN | disclosed |