Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30145233 | 0.85 | ABCB1 (0.59) | MAPTALDH1A1HPGDATMLTA4H | |
| SCHEMBL7914167 | 0.85 | ABCB1 (0.59) | MAPTALDH1A1HPGDATMLTA4H | |
| SCHEMBL1539317 | 0.81 | SMN1; SMN2 (0.47) | MAPTALDH1A1HPGDATMHTT | |
| Alcohol SCHEMBL27562871 | 0.81 | MAPT (0.56) | MAPTALDH1A1HPGDATMHTT | |
| SCHEMBL19140088 | 0.81 | MAPT (0.52) | MAPTALDH1A1HPGDATMHTT | |
| SCHEMBL29414783 | 0.80 | MAPT (0.59) | MAPTALDH1A1HPGDATMLTA4H | |
| SCHEMBL1081189 | 0.80 | MAPT (0.59) | MAPTALDH1A1HPGDATMLTA4H | |
| SCHEMBL74492 | 0.80 | HTR7 (0.57) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL31259416 | 0.80 | HTR7 (0.57) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL1928044 | 0.79 | MAOB (0.53) | MAPTALDH1A1HPGDATMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332948-A | Nitrogen-containing tetracyclic compound, preparation method and medicinal application thereof | 翰森生物有限责任公司 | 2023-06-27 | — | — | CN | disclosed |