Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24806290 | 1.00 | KMT2A (0.42) | KMT2ASTAT3MAPTSMN1; SMN2HRH4 | |
| SCHEMBL30047462 | 0.85 | STAT3 (0.45) | KMT2ASTAT3MAPTSMN1; SMN2POLB | |
| SCHEMBL24814724 | 0.85 | STAT3 (0.45) | KMT2ASTAT3MAPTSMN1; SMN2POLB | |
| SCHEMBL30047664 | 0.82 | MAPT (0.43) | KMT2ASTAT3MAPTSMN1; SMN2POLB | |
| SCHEMBL30146511 | 0.82 | STAT3 (0.38) | KMT2ASTAT3MAPTSMN1; SMN2POLB | |
| SCHEMBL24806293 | 0.81 | STAT3 (0.36) | KMT2ASTAT3MAPTSMN1; SMN2 | |
| SCHEMBL30146462 | 0.81 | STAT3 (0.36) | KMT2ASTAT3MAPTSMN1; SMN2 | |
| SCHEMBL24807043 | 0.81 | HTR2C (0.32) | KMT2AMAPTKDM4ERETNPSR1 | |
| SCHEMBL30146431 | 0.81 | HTR2C (0.32) | KMT2AMAPTKDM4ERETNPSR1 | |
| SCHEMBL24807752 | 0.79 | STAT3 (0.35) | KMT2ASTAT3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359413-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022271650-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-12-29 | — | — | WO | disclosed |