Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30047462 | 1.00 | STAT3 (0.45) | STAT3KMT2AMAPTHPGDHSD17B10 | |
| SCHEMBL30146511 | 0.87 | STAT3 (0.38) | STAT3KMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL29909809 | 0.86 | MAPT (0.38) | STAT3KMT2AMAPTHPGDHSD17B10 | |
| SCHEMBL23576783 | 0.86 | MAPT (0.38) | STAT3KMT2AMAPTHPGDHSD17B10 | |
| SCHEMBL24806290 | 0.85 | KMT2A (0.42) | STAT3KMT2AMAPTHPGDHSD17B10 | |
| SCHEMBL30146450 | 0.85 | KMT2A (0.42) | STAT3KMT2AMAPTHPGDHSD17B10 | |
| SCHEMBL30047664 | 0.85 | MAPT (0.43) | STAT3KMT2AMAPTHPGDHSD17B10 | |
| SCHEMBL23601720 | 0.84 | KMT2A (0.63) | STAT3KMT2AMAPTHPGDHSD17B10 | |
| SCHEMBL30979080 | 0.84 | KMT2A (0.63) | STAT3KMT2AMAPTHPGDHSD17B10 | |
| SCHEMBL23577278 | 0.83 | MAPT (0.39) | STAT3KMT2AMAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355531-A | Diacylglycerol kinase modulating compounds | 吉利德科学公司 | 2024-01-05 | — | — | CN | disclosed |
| WO-2022271684-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-12-29 | — | — | WO | disclosed |