⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6378659 | 0.98 | — | — | |
| SCHEMBL6373860 | 0.76 | USP2 (0.32) | — | |
| SCHEMBL7094787 | 0.70 | — | — | |
| SCHEMBL4322762 | 0.70 | TYMS (0.39) | — | |
| SCHEMBL27545565 | 0.70 | — | — | |
| SCHEMBL6375020 | 0.68 | — | — | |
| SCHEMBL27892994 | 0.67 | HIF1A (0.32) | — | |
| Fosmidomycin SCHEMBL301404 | 0.67 | TYMS (0.48) | — | |
| Fosmidomycin SCHEMBL11438018 | 0.65 | TYMS (0.46) | — | |
| Fosmidomycin SCHEMBL4432380 | 0.65 | TYMS (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3960176-A1 | PIPERAQUINE AND RELATED DRUG COMBINATIONS FOR USE IN THE TREATMENT OF COVID-19 | DMG Deutsche Malaria GmbH (DE) | 2022-03-02 | — | — | EP | disclosed |
| EP-2590651-B1 | NEW DRUG COMBINATIONS FOR THE TREATMENT OF MALARIA | BIOAGENCY AG (DE) | 2018-06-27 | — | — | EP | disclosed |
| US-20130231296-A1 | NEW DRUG COMBINATIONS FOR THE TREATMENT OF MALARIA | BIOAGENCY AG (DE) | 2013-09-05 | — | — | US | disclosed |
| EP-2590651-A1 | NEW DRUG COMBINATIONS FOR THE TREATMENT OF MALARIA | BioAgency AG (DE) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004324-A1 | NEW DRUG COMBINATIONS FOR THE TREATMENT OF MALARIA | BIOAGENCY AG (DE) | 2012-01-12 | — | — | WO | disclosed |
| EP-2404601-A1 | New drug combinations for the treatment of Malaria | BioAgency AG (DE) | 2012-01-11 | — | — | EP | disclosed |
| US-20050075511-A1 | Phosphorous organic compounds and their use | JOMAA HASSAN (DE) | 2005-04-07 | — | — | US | disclosed |
| US-6812224-B2 | A FUNGICIDE, BACTERICIDE TREATING INFECTIONS IN HUMANS, ANIMALS, PLANTS AND HERBICIDE IN PLANTS | JOMAA PHARMAKA GMBH (DE) | 2004-11-02 | — | — | US | disclosed |
| US-6753324-B2 | USED IN INFECTIONS BY VIRUSES, BACTERIA, FUNGI, AND PARASITES | JOMAA HASSAN (DE) | 2004-06-22 | — | — | US | disclosed |
| US-20030045746-A1 | Phosphorous organic compounds and their use | JOMAA PHARMAKA GMBH (DE) | 2003-03-06 | — | — | US | disclosed |
| US-20030036533-A1 | Phosphorous organic compounds and their use | JOMAA PHARMAKA GMBH (DE) | 2003-02-20 | — | — | US | disclosed |
| EP-1095050-A1 | PHOSPHOROUS ORGANIC COMPOUNDS AND THEIR USE | Jomaa, Hassan (DE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000004031-A1 | PHOSPHOROUS ORGANIC COMPOUNDS AND THEIR USE | JOMAA HASSAN (DE) | 2000-01-27 | — | — | WO | disclosed |