⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941914 | 0.88 | HDAC2 (0.41) | — | |
| SCHEMBL4825533 | 0.84 | HDAC2 (0.50) | — | |
| SCHEMBL4825529 | 0.72 | CNR1 (0.35) | — | |
| SCHEMBL24355143 | 0.70 | — | — | |
| SCHEMBL301468 | 0.70 | — | — | |
| SCHEMBL8590466 | 0.70 | ALDH1A1 (0.31) | — | |
| SCHEMBL899927 | 0.69 | TDP1 (0.37) | — | |
| SCHEMBL16792232 | 0.68 | CAMK2A (0.46) | — | |
| SCHEMBL20998889 | 0.67 | TDP1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL9711107 | 0.67 | ALOX15 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815084-B1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | EP | disclosed |