Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.47 |
| ▸ | TYK2 | P29597 | 13/20 | 0.47 |
| ▸ | JAK3 | P52333 | 13/20 | 0.47 |
| ▸ | JAK1 | P23458 | 12/20 | 0.47 |
| ▸ | JAK2 | O60674 | 11/20 | 0.47 |
| ▸ | AURKA | O14965 | 2/20 | 0.40 |
| ▸ | PLK4 | O00444 | 2/20 | 0.38 |
| ▸ | PAK4 | O96013 | 2/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23889580 | 1.00 | GPR119 (0.47) | GPR119TYK2JAK3JAK1JAK2 | |
| SCHEMBL23878737 | 0.90 | TYK2 (0.45) | TYK2JAK3JAK1JAK2AURKA | |
| SCHEMBL30147210 | 0.88 | GPR119 (0.47) | GPR119TYK2JAK3JAK1JAK2 | |
| SCHEMBL22055044 | 0.88 | GPR119 (0.47) | GPR119TYK2JAK3JAK1JAK2 | |
| SCHEMBL22054573 | 0.86 | GPR119 (0.53) | GPR119TYK2JAK3JAK1JAK2 | |
| SCHEMBL22054197 | 0.86 | GPR119 (0.52) | GPR119TYK2JAK3JAK1JAK2 | |
| SCHEMBL30147229 | 0.86 | GPR119 (0.53) | GPR119TYK2JAK3JAK1JAK2 | |
| SCHEMBL30147224 | 0.86 | GPR119 (0.52) | GPR119TYK2JAK3JAK1JAK2 | |
| SCHEMBL22055034 | 0.85 | GPR119 (0.55) | GPR119TYK2JAK3JAK1JAK2 | |
| SCHEMBL30147236 | 0.85 | GPR119 (0.55) | GPR119TYK2JAK3JAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003441-B | Heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2025-06-10 | — | — | CN | disclosed |
| CN-115925705-B | Heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-116003441-A | Heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-115925705-A | Heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-115667228-A | Salt and crystal form of heteroaromatic derivative and preparation method of salt and crystal form | 上海翰森生物医药科技有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-111511738-B | Heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2023-01-20 | — | — | CN | disclosed |