Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 4/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | F12 | P00748 | 2/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30147601 | 0.88 | PARP1 (0.49) | ESR2TRPV1NR1H2PARP1MKNK1 | |
| SCHEMBL2270578 | 0.84 | PARP1 (0.57) | TRPV1PARP1FAAHTNKS2PARP2 | |
| SCHEMBL27002298 | 0.84 | ESR2 (0.46) | ESR2TRPV1NR1H2PARP1FAAH | |
| SCHEMBL29915037 | 0.84 | ESR2 (0.46) | ESR2TRPV1NR1H2PARP1FAAH | |
| SCHEMBL3476663 | 0.81 | TRPV1 (0.47) | ESR2TRPV1NR1H2FAAHF12 | |
| SCHEMBL23537359 | 0.81 | KDM4E (0.36) | ESR2NR1H2PARP1KDM4EMAPT | |
| SCHEMBL30022693 | 0.81 | KDM4E (0.36) | ESR2NR1H2PARP1KDM4EMAPT | |
| SCHEMBL21588274 | 0.79 | TRPV1 (0.48) | ESR2TRPV1PARP1FAAHF12 | |
| SCHEMBL21588267 | 0.79 | TRPV1 (0.51) | ESR2TRPV1NR1H2FAAHMKNK1 | |
| SCHEMBL21588367 | 0.79 | BAZ2B (0.58) | TRPV1FAAHKDM4EMAPTCDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551864-A | Substituted tricyclic amides, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2022-12-30 | — | — | CN | disclosed |