Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 2/20 | 0.42 |
| ▸ | CCND1 | P24385 | 2/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30147489 | 0.88 | ESR2 (0.43) | PARP1ESR2MKNK1TRPV1NR1H2 | |
| SCHEMBL21588267 | 0.87 | TRPV1 (0.51) | BAZ2BBRD3ESR2MKNK1TRPV1 | |
| SCHEMBL21588367 | 0.87 | BAZ2B (0.58) | BAZ2BBRD3TRPV1CDK4CCND1 | |
| SCHEMBL2270578 | 0.85 | PARP1 (0.57) | PARP1TRPV1CDK4CCND1 | |
| SCHEMBL29915037 | 0.83 | ESR2 (0.46) | PARP1BAZ2BESR2MKNK1TRPV1 | |
| SCHEMBL27002298 | 0.83 | ESR2 (0.46) | PARP1BAZ2BESR2MKNK1TRPV1 | |
| SCHEMBL23537452 | 0.82 | PARP1 (0.39) | PARP1BRD3PLK1 | |
| SCHEMBL29824381 | 0.82 | PARP1 (0.39) | PARP1BRD3PLK1 | |
| SCHEMBL21588363 | 0.79 | CDK9 (0.44) | BRD3ESR2MKNK1TRPV1NR1H2 | |
| SCHEMBL21114805 | 0.78 | BAZ2B (0.58) | BAZ2BBRD3ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551864-A | Substituted tricyclic amides, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2022-12-30 | — | — | CN | disclosed |