Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | GPER1 | Q99527 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13271499 | 0.82 | ALOX15 (0.56) | ALOX15SYKNPC1RAB9APTPN11 | |
| SCHEMBL30147580 | 0.81 | ALOX15 (0.46) | ALOX15SYKNPC1RAB9ARXFP1 | |
| SCHEMBL4397741 | 0.81 | KDM4E (0.56) | ALOX15KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL30147534 | 0.81 | KDM4E (0.56) | ALOX15KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL29824257 | 0.78 | ALOX15 (0.58) | ALOX15SYKNPC1RAB9ARXFP1 | |
| SCHEMBL23147832 | 0.76 | MLLT1 (0.53) | KDRRETROCK2ROCK1MLLT1 | |
| SCHEMBL2814032 | 0.75 | KDM4E (0.58) | ALOX15NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL2760015 | 0.75 | KDM4E (0.66) | ALOX15NPC1RAB9ARXFP1GPER1 | |
| SCHEMBL30147543 | 0.74 | NTRK1 (0.45) | ALOX15GPER1PTPN11NUDT1KMT2A | |
| SCHEMBL30147547 | 0.74 | ALOX15 (0.57) | ALOX15SYKPTPN11KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551864-A | Substituted tricyclic amides, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2022-12-30 | — | — | CN | disclosed |