Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | KCNQ3 | O43525 | 4/20 | 0.51 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.51 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.49 |
| ▸ | CHRNG | P07510 | 1/20 | 0.49 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL531941 | 1.00 | CES2 (0.59) | CES2CES1HDAC6HDAC8HDAC2 | |
| SCHEMBL8515075 | 0.84 | ESRRG (0.50) | HDAC6HDAC8HDAC2HDAC1THRB | |
| SCHEMBL30102019 | 0.84 | HDAC6 (0.53) | HDAC6HDAC8HDAC2HDAC1KCNQ3 | |
| SCHEMBL30147494 | 0.84 | HDAC6 (0.73) | HDAC6HDAC8HDAC2HDAC1KCNQ3 | |
| SCHEMBL1441177 | 0.84 | HDAC6 (0.73) | HDAC6HDAC8HDAC2HDAC1KCNQ3 | |
| SCHEMBL1507188 | 0.84 | HDAC6 (0.53) | HDAC6HDAC8HDAC2HDAC1KCNQ3 | |
| SCHEMBL29306646 | 0.84 | GAA (0.58) | HDAC6HDAC8HDAC2HDAC1THRB | |
| SCHEMBL5019978 | 0.82 | HDAC6 (0.47) | HDAC6HDAC8HDAC2HDAC1THRB | |
| SCHEMBL3819667 | 0.82 | HDAC6 (0.52) | HDAC6HDAC8HDAC2HDAC1THRB | |
| SCHEMBL355600 | 0.82 | HDAC6 (0.71) | HDAC6HDAC8HDAC2HDAC1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227089-B | Substituted 6-azabenzimidazole compounds as HPK1 inhibitors | 吉利德科学公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-115551864-A | Substituted tricyclic amides, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2022-12-30 | — | — | CN | disclosed |