Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 3/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21598433 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1MAPTRECQLDRD2 | |
| SCHEMBL31247608 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1MAPTRECQLDRD2 | |
| SCHEMBL29504673 | 0.77 | ADORA2A (0.44) | KDM4EALDH1A1MAPTRECQLDRD2 | |
| SCHEMBL565864 | 0.74 | KDM4E (0.61) | KDM4EALDH1A1MAPTRECQLDRD2 | |
| SCHEMBL18839501 | 0.74 | MALT1 (0.38) | ALDH1A1MALT1 | |
| SCHEMBL29818410 | 0.74 | MALT1 (0.38) | ALDH1A1MALT1 | |
| SCHEMBL3287137 | 0.74 | KDM4E (0.61) | KDM4EALDH1A1MAPTRECQLDRD2 | |
| SCHEMBL3735595 | 0.74 | CYP2A6 (0.44) | KDM4EALDH1A1MAPTRECQLDRD2 | |
| SCHEMBL6822065 | 0.73 | KDM4E (0.59) | KDM4EALDH1A1MAPTRECQLDRD2 | |
| SCHEMBL30748716 | 0.73 | KDM4E (0.59) | KDM4EALDH1A1MAPTRECQLDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3807266-B1 | PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-25 | — | — | EP | disclosed |
| CN-112585128-B | Pyrazole derivatives as MALT1 inhibitors | 詹森药业有限公司 | 2023-02-21 | — | — | CN | disclosed |