Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 5/20 | 0.57 |
| ▸ | HTR2A | P28223 | 4/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3290416 | 1.00 | KDM4E (0.59) | KDM4EALDH1A1MAPTRECQLDRD2 | |
| SCHEMBL6822065 | 1.00 | KDM4E (0.59) | KDM4EALDH1A1MAPTRECQLDRD2 | |
| SCHEMBL565864 | 0.98 | KDM4E (0.61) | KDM4EALDH1A1MAPTRECQLDRD2 | |
| SCHEMBL3287137 | 0.95 | KDM4E (0.61) | KDM4EALDH1A1MAPTRECQLDRD2 | |
| SCHEMBL3555991 | 0.86 | KDM4E (0.53) | KDM4EALDH1A1MAPTRECQLDRD2 | |
| SCHEMBL27939424 | 0.85 | KDM4E (0.58) | KDM4EALDH1A1MAPTRECQLDRD2 | |
| SCHEMBL2750963 | 0.85 | KDM4E (0.58) | KDM4EALDH1A1MAPTRECQLDRD2 | |
| SCHEMBL2004470 | 0.85 | DRD2 (0.53) | KDM4EALDH1A1MAPTRECQLDRD2 | |
| SCHEMBL3291175 | 0.85 | ALDH1A1 (0.55) | KDM4EALDH1A1MAPTRECQLDRD2 | |
| SCHEMBL3290261 | 0.85 | ALDH1A1 (0.59) | KDM4EALDH1A1MAPTRECQLDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279907-A | Pyrrolidone derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-12-22 | — | — | CN | disclosed |