SCHEMBL301481

SCHEMBL301481

CO[Si]1(C)CCCOCC(CN2CCN(C)CC2)O1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.33
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
HRH1 P35367 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2582384 0.91 GAA (0.35) GAA
SCHEMBL2582307 0.89 GAA (0.40) GAA
SCHEMBL301734 0.87 HRH3 (0.30) HRH3HTR2AHTR2CHRH1
SCHEMBL28721280 0.86 ACHE (0.36)
SCHEMBL301451 0.85 HRH3 (0.34) HRH3HTR2AHTR2CHRH1GAA
SCHEMBL303012 0.83 HTR2A (0.33) HRH3HTR2AHTR2CHRH1GAA
SCHEMBL302108 0.82 HRH3 (0.32) HRH3HTR2AHTR2CHRH1
SCHEMBL301463 0.81 HRH3 (0.32) HRH3
SCHEMBL301478 0.80 HRH3 (0.31) HRH3GAA
SCHEMBL21049518 0.80 HRH3 (0.34) HRH3HTR2AHTR2CHRH1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209190-A1 CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, RUBBER-CROSSLINKED SUBSTANCE, AND TIRE ZS ELASTOMERS CO., LTD. (JP) 2024-06-27 US disclosed
EP-3505557-B1 RUBBER CROSSLINKED PRODUCT ZEON CORP (JP) 2024-05-01 EP disclosed
EP-4331862-A1 CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, RUBBER-CROSSLINKED SUBSTANCE, AND TIRE ZS Elastomers Co., Ltd. (JP) 2024-03-06 EP disclosed
US-20230374182-A1 CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, CROSSLINKED RUBBER PRODUCT, AND TIRE ZS ELASTOMERS CO., LTD. (JP) 2023-11-23 US disclosed
US-20230365728-A1 CONJUGATED-DIENE-BASED POLYMER, RUBBER COMPOSITION, CROSS-LINKED RUBBER OBJECT, AND TIRE ZS ELASTOMERS CO., LTD. (JP) 2023-11-16 US disclosed
EP-4230432-A1 CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, CROSSLINKED RUBBER PRODUCT, AND TIRE ZS Elastomers Co., Ltd. (JP) 2023-08-23 EP disclosed
EP-4230433-A1 CONJUGATED-DIENE-BASED POLYMER, RUBBER COMPOSITION, CROSS-LINKED RUBBER OBJECT, AND TIRE ZS Elastomers Co., Ltd. (JP) 2023-08-23 EP disclosed
CN-116472185-A Conjugated diene polymer, rubber composition, rubber crosslinked product, and tire 瑞住合成橡胶株式会社 2023-07-21 CN disclosed
CN-116323246-A Conjugated diene polymer, rubber composition, rubber crosslinked product, and tire 瑞住合成橡胶株式会社 2023-06-23 CN disclosed
EP-3495394-B1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING POLYMER COMPOSITION SUMITOMO CHEMICAL CO (JP) 2023-04-12 EP disclosed
US-9982065-B2 Method of production of conjugated diene rubber ZEON CORPORATION (JP) 2018-05-29 US disclosed
EP-3315535-A1 METHOD OF PRODUCTION OF CONJUGATED DIENE RUBBER Zeon Corporation (JP) 2018-05-02 EP disclosed
EP-3309181-A1 CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCTION CONJUGATED DIENE POLYMER Zeon Corporation (JP) 2018-04-18 EP disclosed
US-20170137555-A1 METHOD OF PRODUCTION OF CONJUGATED DIENE RUBBER ZEON CORPORATION (JP) 2017-05-18 US disclosed
EP-3162814-A1 METHOD FOR MANUFACTURING CONJUGATED DIENE RUBBER Zeon Corporation (JP) 2017-05-03 EP disclosed
EP-2404924-B1 Aqueous solution of piperazinyl-containing silanol compound and making method SHINETSU CHEMICAL CO (JP) 2013-03-20 EP disclosed
US-20120006229-A1 AQUEOUS SOLUTION OF PIPERAZINYL-CONTAINING SILANOL COMPOUND AND MAKING METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-01-12 US disclosed
EP-2404924-A1 Aqueous solution of piperazinyl-containing silanol compound and making method Shin-Etsu Chemical Co., Ltd. (JP) 2012-01-11 EP disclosed
US-8049027-B2 Organosilicon compound having amino group and its production method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-11-01 US disclosed
US-20100099866-A1 ORGANOSILICON COMPOUND HAVING AMINO GROUP AND ITS PRODUCTION METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099866-A1 ORGANOSILICON COMPOUND HAVING AMINO GROUP AND ITS PRODUCTION METHOD HRH3, H1-0, H1-2 HRH3 1/4885HTR2A 927/4885HTR2C 851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.