SCHEMBL30148434

SCHEMBL30148434

CC(C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 5/20 0.54
▸ NPY1R P25929 3/20 0.50
▸ NPY2R P49146 3/20 0.50
▸ NPY4R P50391 3/20 0.50
▸ IL23R Q5VWK5 2/20 0.50
▸ ACE P12821 2/20 0.50
▸ PRMT1 Q99873 1/20 0.50
▸ MAGI3 Q5TCQ9 1/20 0.49
▸ ECE1 P42892 1/20 0.49
▸ C5AR1 P21730 1/20 0.49
▸ CD47 Q08722 1/20 0.49
▸ SIRT5 Q9NXA8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29799939 1.00 KISS1R (0.54) KISS1RNPY1RNPY2RNPY4RIL23R
SCHEMBL30305322 1.00 KISS1R (0.54) KISS1RNPY1RNPY2RNPY4RIL23R
SCHEMBL30305637 1.00 KISS1R (0.54) KISS1RNPY1RNPY2RNPY4RIL23R
SCHEMBL30305270 1.00 KISS1R (0.54) KISS1RNPY1RNPY2RNPY4RIL23R
SCHEMBL30456528 1.00 KISS1R (0.54) KISS1RNPY1RNPY2RNPY4RIL23R
SCHEMBL30305302 1.00 KISS1R (0.54) KISS1RNPY1RNPY2RNPY4RIL23R
SCHEMBL30340404 1.00 KISS1R (0.54) KISS1RNPY1RNPY2RNPY4RIL23R
SCHEMBL29732503 1.00 KISS1R (0.54) KISS1RNPY1RNPY2RNPY4RIL23R
SCHEMBL29732780 1.00 KISS1R (0.54) KISS1RNPY1RNPY2RNPY4RIL23R
SCHEMBL30092900 0.98 KISS1R (0.54) KISS1RNPY1RNPY2RNPY4RIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4401752-A1 ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF Peptilogics, Inc. (US) 2024-07-24 — — EP claimed
WO-2023044423-A1 ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF PEPTILOGICS, INC. (US) 2023-03-23 — — WO claimed
US-20250320266-A1 Methods and Compositions for Treatment of Antibiotic-Resistant Bacterial Infections UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) 2025-10-16 — — US disclosed
US-12371463-B2 Methods and compositions for treatment of antibiotic-resistant bacterial infections University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2025-07-29 — — US disclosed
EP-4401752-A1 ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF Peptilogics, Inc. (US) 2024-07-24 — — EP disclosed
WO-2023044423-A1 ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF PEPTILOGICS, INC. (US) 2023-03-23 — — WO disclosed
US-20220332777-A1 Methods and Compositions for Treatment of Antibiotic-Resistant Bacterial Infections UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2022-10-20 — — US disclosed
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