Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.53 |
| ▸ | IL23R | Q5VWK5 | 10/20 | 0.51 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.51 |
| ▸ | CTSC | P53634 | 1/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.48 |
| ▸ | GHSR | Q92847 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30305641 | 1.00 | MAGI3 (0.53) | MAGI3IL23RKISS1RCTSCSIRT5 | |
| SCHEMBL30945413 | 1.00 | MAGI3 (0.53) | MAGI3IL23RKISS1RCTSCSIRT5 | |
| SCHEMBL31065007 | 0.98 | MAGI3 (0.52) | MAGI3IL23RKISS1RCTSCGHSR | |
| SCHEMBL30093039 | 0.97 | IL23R (0.51) | MAGI3IL23RKISS1RCTSCSIRT5 | |
| SCHEMBL30093123 | 0.97 | IL23R (0.51) | MAGI3IL23RKISS1RCTSCSIRT5 | |
| SCHEMBL30339793 | 0.97 | IL23R (0.51) | MAGI3IL23RKISS1RCTSCSIRT5 | |
| SCHEMBL30302924 | 0.97 | IL23R (0.51) | MAGI3IL23RKISS1RCTSCSIRT5 | |
| SCHEMBL30302936 | 0.97 | IL23R (0.51) | MAGI3IL23RKISS1RCTSCSIRT5 | |
| SCHEMBL29799990 | 0.97 | IL23R (0.51) | MAGI3IL23RKISS1RCTSCSIRT5 | |
| SCHEMBL30305362 | 0.97 | IL23R (0.51) | MAGI3IL23RKISS1RCTSCSIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023044487-A1 | TREATMENT OF LUNG DISEASE OR INJURY USING ENGINEERED ANTIMICROBIAL PEPTIDES | PEPTILOGICS, INC. (US) | 2023-03-23 | — | — | WO | claimed |
| US-20250320266-A1 | Methods and Compositions for Treatment of Antibiotic-Resistant Bacterial Infections | UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) | 2025-10-16 | — | — | US | disclosed |
| US-20250277002-A1 | ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES AND METHODS OF USE | PEPTILOGICS, INC. | 2025-09-04 | — | — | US | disclosed |
| US-12371463-B2 | Methods and compositions for treatment of antibiotic-resistant bacterial infections | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2025-07-29 | — | — | US | disclosed |
| EP-4401752-A1 | ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF | Peptilogics, Inc. (US) | 2024-07-24 | — | — | EP | disclosed |
| US-20230107222-A1 | ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES AND METHODS OF USE | PEPTILOGICS, INC. | 2023-04-06 | — | — | US | disclosed |
| WO-2023044423-A1 | ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF | PEPTILOGICS, INC. (US) | 2023-03-23 | — | — | WO | disclosed |
| US-20220332777-A1 | Methods and Compositions for Treatment of Antibiotic-Resistant Bacterial Infections | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2022-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250277002-A1 | ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES AND METHODS OF USE | NGLY1, PRF1, LNPEP | MAGI3 3116/4885IL23R 2492/4885KISS1R 3536/4885 |
| US-20230107222-A1 | ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES AND METHODS OF USE | NGLY1, PRF1, LNPEP | MAGI3 3116/4885IL23R 2492/4885KISS1R 3536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.