Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 5/20 | 0.42 |
| ▸ | NPY4R | P50391 | 14/20 | 0.42 |
| ▸ | NPY1R | P25929 | 9/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.42 |
| ▸ | NPY2R | P49146 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30305283 | 1.00 | FURIN (0.42) | FURINNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29732279 | 1.00 | FURIN (0.42) | FURINNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30148440 | 1.00 | FURIN (0.42) | FURINNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30305323 | 1.00 | FURIN (0.42) | FURINNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29732620 | 1.00 | FURIN (0.42) | FURINNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30302888 | 1.00 | FURIN (0.42) | FURINNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30305282 | 1.00 | FURIN (0.42) | FURINNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30945395 | 1.00 | FURIN (0.42) | FURINNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL31110537 | 1.00 | FURIN (0.42) | FURINNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29799967 | 1.00 | FURIN (0.42) | FURINNPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4401752-A1 | ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF | Peptilogics, Inc. (US) | 2024-07-24 | — | — | EP | claimed |
| WO-2023044423-A1 | ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF | PEPTILOGICS, INC. (US) | 2023-03-23 | — | — | WO | claimed |
| WO-2023044487-A1 | TREATMENT OF LUNG DISEASE OR INJURY USING ENGINEERED ANTIMICROBIAL PEPTIDES | PEPTILOGICS, INC. (US) | 2023-03-23 | — | — | WO | claimed |
| US-20250320266-A1 | Methods and Compositions for Treatment of Antibiotic-Resistant Bacterial Infections | UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) | 2025-10-16 | — | — | US | disclosed |
| US-20250277002-A1 | ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES AND METHODS OF USE | PEPTILOGICS, INC. | 2025-09-04 | — | — | US | disclosed |
| US-12371463-B2 | Methods and compositions for treatment of antibiotic-resistant bacterial infections | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2025-07-29 | — | — | US | disclosed |
| EP-4401752-A1 | ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF | Peptilogics, Inc. (US) | 2024-07-24 | — | — | EP | disclosed |
| US-20230107222-A1 | ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES AND METHODS OF USE | PEPTILOGICS, INC. | 2023-04-06 | — | — | US | disclosed |
| WO-2023044423-A1 | ENGINEERED ANTIMICROBIAL PEPTIDES AND USAGE THEREOF | PEPTILOGICS, INC. (US) | 2023-03-23 | — | — | WO | disclosed |
| WO-2023044487-A1 | TREATMENT OF LUNG DISEASE OR INJURY USING ENGINEERED ANTIMICROBIAL PEPTIDES | PEPTILOGICS, INC. (US) | 2023-03-23 | — | — | WO | disclosed |
| US-20220332777-A1 | Methods and Compositions for Treatment of Antibiotic-Resistant Bacterial Infections | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2022-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250277002-A1 | ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES AND METHODS OF USE | NGLY1, PRF1, LNPEP | FURIN 970/4885NPY4R 3510/4885NPY1R 3504/4885 |
| US-20230107222-A1 | ENGINEERED ANTIMICROBIAL AMPHIPHILIC PEPTIDES AND METHODS OF USE | NGLY1, PRF1, LNPEP | FURIN 970/4885NPY4R 3510/4885NPY1R 3504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.