Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522265 | 1.00 | MAPT (0.44) | MAPTTSHRALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL1352722 | 0.85 | NOTUM (0.48) | TSHRALDH1A1KDM4ENOTUMRAB9A | |
| SCHEMBL30675636 | 0.85 | NOTUM (0.48) | TSHRALDH1A1KDM4ENOTUMRAB9A | |
| SCHEMBL16957794 | 0.84 | TSHR (0.45) | MAPTTSHRALDH1A1KDM4ENOTUM | |
| SCHEMBL11446278 | 0.83 | TSHR (0.41) | MAPTTSHRALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13254942 | 0.83 | PARP1 (0.45) | MAPTTSHRALDH1A1KDM4ERAB9A | |
| SCHEMBL180961 | 0.82 | ALDH1A1 (0.48) | MAPTTSHRALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11113016 | 0.81 | CXCR2 (0.44) | MAPTTSHRALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL646271 | 0.80 | ALDH1A1 (0.50) | TSHRALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL30506574 | 0.80 | ALDH1A1 (0.50) | TSHRALDH1A1SMN1; SMN2KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137507-A1 | SOS1 INHIBITORS AND USES THEREOF | REGOR PHARMACEUTICALS, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| WO-2022268209-A1 | DERIVATIVE HAVING PYRIMIDINE-FUSED CYCLIC STRUCTURE, AND USE THEREOF | 四川汇宇制药股份有限公司 | 2022-12-29 | — | — | WO | disclosed |