Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | THPO | P40225 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | STAT6 | P42226 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11025931 | 0.69 | MAPK1 (0.43) | MAPK1TP53NFKB1THPOGMNN | |
| SCHEMBL8239850 | 0.67 | MAPK1 (0.41) | MAPK1TP53NFKB1THPOGMNN | |
| SCHEMBL1810331 | 0.67 | MAPK1 (0.41) | MAPK1TP53NFKB1THPOGMNN | |
| SCHEMBL18185730 | 0.67 | MAPK1 (0.50) | MAPK1TP53NFKB1THPOGMNN | |
| SCHEMBL15995542 | 0.67 | MAPK1 (0.41) | MAPK1TP53NFKB1THPOGMNN | |
| SCHEMBL19434761 | 0.63 | MAPK1 (0.37) | MAPK1TP53NFKB1THPOGMNN | |
| SCHEMBL16904324 | 0.63 | MAPK1 (0.37) | MAPK1TP53NFKB1THPOGMNN | |
| SCHEMBL14476696 | 0.63 | ALOX15 (0.39) | MAPK1TP53NFKB1THPOGMNN | |
| SCHEMBL19450480 | 0.63 | MAPK1 (0.37) | MAPK1TP53NFKB1THPOGMNN | |
| SCHEMBL16457638 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521325-A | Boronic acid derivatives | 首药控股(北京)股份有限公司 | 2022-12-27 | — | — | CN | disclosed |