SCHEMBL301499

SCHEMBL301499

C=CCOC(=O)c1cccc(CC=C)c1C(=O)OCC=C

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.63
HSD17B10 Q99714 2/20 0.55
ALDH1A1 P00352 2/20 0.55
TSHR P16473 1/20 0.55
KDM4E B2RXH2 4/20 0.43
GABRA1 P14867 1/20 0.40
GABRB2 P47870 1/20 0.40
RHOA P61586 1/20 0.39
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
MAPT P10636 2/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
MAPK1 P28482 1/20 0.38
SNCA P37840 1/20 0.38
FGFR1 P11362 1/20 0.36
LIG1 P18858 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22418858 0.91 CYP3A4 (0.59) CYP3A4HSD17B10ALDH1A1TSHRKDM4E
SCHEMBL28380144 0.88 CYP3A4 (0.49) CYP3A4HSD17B10ALDH1A1TSHRKDM4E
SCHEMBL29020478 0.88 CYP3A4 (0.49) CYP3A4HSD17B10ALDH1A1TSHRKDM4E
SCHEMBL343095 0.87 CYP3A4 (0.76) CYP3A4HSD17B10ALDH1A1TSHRKDM4E
SCHEMBL8523675 0.87 HSD17B10 (0.57) CYP3A4HSD17B10ALDH1A1TSHRKDM4E
SCHEMBL851234 0.86 CYP3A4 (0.74) CYP3A4HSD17B10ALDH1A1TSHRKDM4E
SCHEMBL496615 0.85 CYP3A4 (0.63) CYP3A4HSD17B10ALDH1A1TSHRKDM4E
SCHEMBL4603952 0.85 CYP3A4 (0.50) CYP3A4HSD17B10ALDH1A1TSHRKDM4E
SCHEMBL8523676 0.84 CYP3A4 (0.58) CYP3A4HSD17B10ALDH1A1TSHRKDM4E
SCHEMBL9279951 0.84 CYP3A4 (0.71) CYP3A4HSD17B10ALDH1A1TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 924 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024072763-A1 FLAME RETARDANT ACRYLIC POWDER COMPOSITION ROHM AND HAAS COMPANY (US) 2024-04-04 WO claimed
WO-2024072762-A1 FLAME RETARDANT ACRYLIC POWDER COMPOSITION ROHM AND HAAS COMPANY (US) 2024-04-04 WO claimed
WO-2024072764-A1 PROCESS FOR PREPARING A FLAME RETARDANT ACRYLIC POWDER COMPOSITION ROHM AND HAAS COMPANY (US) 2024-04-04 WO claimed
US-11667781-B2 Polyvinyl chloride compositions containing impact modifiers and calcium carbonate DOW GLOBAL TECHNOLOGIES, LLC (US) 2023-06-06 US claimed
EP-3464389-B1 MULTI-STAGE POLYMER COMPOSITION AND FILMS MADE THEREFROM ROHM & HAAS (US) 2023-01-25 EP claimed
CN-110741040-B Polyvinyl chloride composition containing impact modifier and calcium carbonate 陶氏环球技术有限责任公司 2022-05-17 CN claimed
US-20220145243-A1 POROUS CELLULAR SCAFFOLD COMPRISING SERUM-DERIVED PROTEIN, AND PRODUCTION METHOD THEREFOR DANAGREEN CO., LTD. (KR) 2022-05-12 US claimed
EP-2681615-B1 SILICONE HYDROGEL CONTACT LENSES AND METHOD OF MANUFACTURING THE SAME COOPERVISION INT LTD (GB) 2021-12-15 EP claimed
EP-3916080-A1 POROUS CELLULAR SCAFFOLD COMPRISING SERUM-DERIVED PROTEIN, AND PRODUCTION METHOD THEREFOR Danagreen Co., Ltd. (KR) 2021-12-01 EP claimed
CN-109153742-B Multi-stage polymer compositions and films made therefrom 罗门哈斯公司 2021-11-30 CN claimed
US-20020128346-A1 Cell growth substrate polymer that is obtainable by copolymerizing a sulfo-containing monomer with a nonsulfo-containing monomer, optionally with a photoinitiator; especially photopolymerizing DOMSCHKE ANGELIKA MARIA (US) 2002-09-12 US claimed
WO-2001049824-A2 CELL GROWTH SUBSTRATE HYDROGELS NOVARTIS AG (CH) 2001-07-12 WO claimed
EP-0832142-B1 POLYMERIZABLE SILOXANE MACROMONOMERS NOVARTIS AG (CH) 2001-07-11 EP claimed
US-6043328-A MOLDINGS, CONTACT LENSES, CORNEAL IMPLANTS OR BIOMEDICAL ARTICLES, NOVARTIS AG (CH) 2000-03-28 US claimed
US-5981615-A Polymerizable siloxane macromonomers CIBA VISION CORPORATION (US) 1999-11-09 US claimed
EP-0826158-B1 POLYSILOXANE-POLYOL MACROMERS, THEIR PREPARATION AND THEIR USE NOVARTIS AG (CH) 1999-09-15 EP claimed
EP-0826158-A1 POLYSILOXANE-POLYOL MACROMERS, THEIR PREPARATION AND THEIR USE Novartis AG (CH) 1998-03-04 EP claimed
WO-1996036890-A1 POLYSILOXANE-POLYOL MACROMERS, THEIR PREPARATION AND THEIR USE NOVARTIS AG (CH) 1996-11-21 WO claimed
US-4795234-A Reinforced optical fiber UBE-NITTO KASEI CO., LTD. (JP) 1989-01-03 US claimed
US-4560729-A MIXTURES OF UNSATURATED NITRILE, PEROXY VULCANIZER, AND CROSSLINKING AGENT NIPPON ZEON CO. LTD. (JP) 1985-12-24 US claimed