SCHEMBL8523675

SCHEMBL8523675

C=CCc1cccc(C(=O)OCC)c1C(=O)OCC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.57
KDM4E B2RXH2 3/20 0.57
TSHR P16473 2/20 0.53
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
ALDH1A1 P00352 4/20 0.46
CYP3A4 P08684 2/20 0.45
CDC25B P30305 2/20 0.43
LMNA P02545 3/20 0.43
MAPK1 P28482 1/20 0.43
POLB P06746 1/20 0.42
MAPT P10636 3/20 0.41
CYP1A2 P05177 2/20 0.41
GAA P10253 2/20 0.41
MEN1 O00255 2/20 0.41
USP2 O75604 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL301499 0.87 CYP3A4 (0.63) HSD17B10KDM4ETSHRALDH1A1CYP3A4
SCHEMBL4251896 0.86 TSHR (0.62) HSD17B10KDM4ETSHRALDH1A1CYP3A4
Glycolic Acid SCHEMBL27438935 0.86 TSHR (0.50) HSD17B10KDM4ETSHRCA12CA1
SCHEMBL8523676 0.86 CYP3A4 (0.58) HSD17B10KDM4ETSHRCA12CA1
SCHEMBL2137984 0.84 TSHR (0.63) HSD17B10KDM4ETSHRCA12CA1
SCHEMBL3689460 0.82 KDM4E (0.46) HSD17B10KDM4ETSHRCA12CA1
SCHEMBL10458544 0.82 ALDH1A1 (0.54) HSD17B10KDM4ETSHRALDH1A1CYP3A4
SCHEMBL560709 0.81 TSHR (0.73) HSD17B10KDM4ETSHRCA12CA1
SCHEMBL11355913 0.80 GABRA1 (0.42) HSD17B10KDM4ETSHRALDH1A1CYP3A4
SCHEMBL10589872 0.79 ALDH1A1 (0.64) HSD17B10KDM4ETSHRCA2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100376619-C Preparation method of viscous liquid and preparation method of cellulose triacetate film FUJI PHOTO FILM CO LTD (JP) 2008-03-26 CN disclosed
CN-100358940-C Method for preparing dope and method for producing cellulose triacetate film FUJI PHOTO FILM CO LTD (JP) 2008-01-02 CN disclosed
CN-1715315-A Method for preparing dope and method for producing cellulose triacetate film FUJI PHOTO FILM CO LTD (JP) 2006-01-04 CN disclosed
CN-1435440-A Preparation method of viscous liquid and preparation method of cellulose triacetate film FUJI PHOTO FILM CO LTD (JP) 2003-08-13 CN disclosed
CN-1230968-A Process for polymerization of 'alpha'-olefins, catalyst used in polymerization and its preparation BOREALIS POLYMERS OY (FI) 1999-10-06 CN disclosed
EP-0927202-A1 PROCESS FOR THE POLYMERIZATION OF $g(a)-OLEFINS, A CATALYST USED IN THE POLYMERIZATION AND ITS PREPARATION BOREALIS POLYMERS OY (FI) 1999-07-07 EP disclosed
WO-1998012234-A1 PROCESS FOR THE POLYMERIZATION OF α-OLEFINS, A CATALYST USED IN THE POLYMERIZATION AND ITS PREPARATION BOREALIS POLYMERS OY (FI) 1998-03-26 WO disclosed