SCHEMBL301507

SCHEMBL301507

C=C(C)C(=O)OCCOCCC#N

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.59
TSHR P16473 7/20 0.44
ALDH1A1 P00352 6/20 0.36
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
TP53 P04637 2/20 0.34
HIF1A Q16665 2/20 0.34
HSD17B10 Q99714 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8698549 1.00 THRB (0.59) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL33780 0.89 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL8217478 0.88 THRB (0.74) THRBTSHRALDH1A1POLBAPEX1
Water SCHEMBL27671456 0.87 THRB (0.76) THRBTSHRALDH1A1POLBAPEX1
Acetic Acid SCHEMBL28158415 0.85 THRB (0.48) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL672102 0.84 THRB (0.79) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL4950550 0.84 THRB (0.79) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL2367616 0.84 THRB (0.79) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL9314009 0.84 THRB (0.79) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL22166147 0.84 THRB (0.79) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5409967-A A shell-core polymer blend ROHM AND HAAS COMPANY (US) 1995-04-25 US claimed
EP-0577281-A2 Amorphous, aromatic polyester containing impact modifier ROHM AND HAAS COMPANY (US) 1994-01-05 EP claimed
JP-4183705-A None JP disclosed
CN-108368331-B Thermoplastic composition with low gloss and high impact strength 科思创有限公司 2022-05-13 CN disclosed
EP-2265665-B1 FUNCTIONAL MBS IMPACT MODIFIERS FOR USE IN ENGINEERING RESINS ARKEMA INC (US) 2021-10-20 EP disclosed
EP-3387068-B1 THERMOPLASTIC COMPOSITIONS HAVING LOW GLOSS AND HIGH IMPACT STRENGTH COVESTRO LLC (US) 2020-10-28 EP disclosed
US-10640672-B2 Acrylic photovoltaic module backsheet ARKEMA FRANCE (FR) 2020-05-05 US disclosed
US-20190177450-A1 FUNCTIONALIZED BIMODAL IMPACT MODIFIERS ARKEMA INC (US) 2019-06-13 US disclosed
US-10308805-B2 Thermoplastic compositions having low gloss and high impact strength COVESTRO LLC (US) 2019-06-04 US disclosed
EP-3387068-A1 THERMOPLASTIC COMPOSITIONS HAVING LOW GLOSS AND HIGH IMPACT STRENGTH Covestro LLC (US) 2018-10-17 EP disclosed
EP-2927252-B1 FUNCTIONALIZED BIMODAL IMPACT MODIFIERS ARKEMA INC (US) 2018-10-10 EP disclosed
EP-1085050-A1 Modified san resin blend composition and articles produced therefrom ROHM AND HAAS COMPANY (US) 2001-03-21 EP disclosed
US-6130290-A FOR INCREASING IMPACT RESISTANCE OF POLYESTERS; OPTICAL CLARITY ROHM AND HAAS COMPANY (US) 2000-10-10 US disclosed
EP-0953583-A2 Impact modifier for amorphous aromatic polyester ROHM AND HAAS COMPANY (US) 1999-11-03 EP disclosed
US-5409967-A A shell-core polymer blend ROHM AND HAAS COMPANY (US) 1995-04-25 US disclosed
US-5321056-A Amorphous, aromatic polyester containing impact modifier ROHM AND HAAS COMPANY (US) 1994-06-14 US disclosed
EP-0577281-A2 Amorphous, aromatic polyester containing impact modifier ROHM AND HAAS COMPANY (US) 1994-01-05 EP disclosed
JP-H04183705-A CYANO GROUP-CONTAINING (METH)ACRYLATE ESTER MIXTURE TOSOH CORP 1992-06-30 JP disclosed
US-4360540-A COATINGS, ADHESIVES ROHM AND HAAS COMPANY (US) 1982-11-23 US disclosed
US-4333963-A FOR SOLVENT RESISTANT ACRYLATE COATINGS ROHM AND HAAS COMPANY (US) 1982-06-08 US disclosed