Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 16/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 12/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18528800 | 0.89 | FFAR4 (0.54) | FFAR4FFAR1CYP2C9CACNA1CPOLB | |
| SCHEMBL1561518 | 0.84 | FFAR4 (0.51) | FFAR4FFAR1CYP2C9CACNA1CALKBH1 | |
| SCHEMBL30343673 | 0.81 | POLB (0.69) | FFAR4FFAR1POLB | |
| SCHEMBL20472384 | 0.81 | TRPV1 (0.57) | FFAR4FFAR1TRPV1 | |
| SCHEMBL1561427 | 0.81 | FFAR4 (0.46) | FFAR4FFAR1CYP2C9CACNA1CALKBH1 | |
| SCHEMBL6902374 | 0.79 | ELANE (0.47) | FFAR4FFAR1CYP2C9CACNA1CPOLB | |
| SCHEMBL20472377 | 0.79 | TAAR1 (0.47) | FFAR4FFAR1ALKBH1TRPV1 | |
| SCHEMBL513139 | 0.78 | FFAR4 (0.48) | FFAR4FFAR1CYP2C9CACNA1CSCN5A | |
| SCHEMBL30698114 | 0.78 | FFAR4 (0.48) | FFAR4FFAR1CYP2C9CACNA1CSCN5A | |
| SCHEMBL30584101 | 0.78 | FFAR4 (0.45) | FFAR4FFAR1CYP2C9CACNA1CALKBH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551846-B | 1,4,5, 6-tetrahydropyrimidin-2-amine derivatives | ＵＢＥ株式会社 | 2024-03-08 | — | — | CN | claimed |
| WO-2023085396-A1 | PHARMACEUTICAL COMPOSITION FOR PROVIDING TREATMENT FOR OR PREVENTING ALPORT SYNDROME | ＵＢＥ株式会社 | 2023-05-19 | — | — | WO | claimed |
| CN-115551846-A | 1,4,5,6-tetrahydropyrimidin-2-amine derivatives | ＵＢＥ株式会社 | 2022-12-30 | — | — | CN | claimed |
| CN-115551846-B | 1,4,5, 6-tetrahydropyrimidin-2-amine derivatives | ＵＢＥ株式会社 | 2024-03-08 | — | — | CN | disclosed |
| WO-2023085396-A1 | PHARMACEUTICAL COMPOSITION FOR PROVIDING TREATMENT FOR OR PREVENTING ALPORT SYNDROME | ＵＢＥ株式会社 | 2023-05-19 | — | — | WO | disclosed |
| CN-115551846-A | 1,4,5,6-tetrahydropyrimidin-2-amine derivatives | ＵＢＥ株式会社 | 2022-12-30 | — | — | CN | disclosed |