Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 11/20 | 0.44 |
| ▸ | FOS | P01100 | 1/20 | 0.44 |
| ▸ | JUN | P05412 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15780081 | 0.85 | AKT1 (0.50) | CXCR2PPARDPPARAAKT1POLB | |
| SCHEMBL10909359 | 0.83 | POLB (0.60) | ELANEPPARGPPARDPPARAFOS | |
| SCHEMBL6909211 | 0.81 | CXCR2 (0.46) | CXCR2PPARDPPARAAKT1POLB | |
| SCHEMBL13197063 | 0.80 | CXCR2 (0.46) | CXCR2PPARGPPARDPPARAAKT1 | |
| SCHEMBL6902841 | 0.79 | FFAR1 (0.51) | ELANEFFAR1FFAR4FOSJUN | |
| SCHEMBL30151160 | 0.79 | FFAR4 (0.60) | FFAR1FFAR4POLBCYP2C9SCN5A | |
| SCHEMBL18528800 | 0.77 | FFAR4 (0.54) | FFAR1FFAR4POLBCYP2C9SCN5A | |
| SCHEMBL11706717 | 0.77 | KDM4E (0.50) | AKT1KDM4E | |
| SCHEMBL27051460 | 0.76 | CFD (0.59) | POLBKDM4ECYP2C9 | |
| SCHEMBL15434125 | 0.76 | FFAR1 (0.47) | PPARGPPARDPPARAFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1431279-A2 | Fluoride containing aromatic compounds | Bayer Chemicals AG (DE) | 2004-06-23 | — | — | EP | claimed |
| EP-1431279-A2 | Fluoride containing aromatic compounds | Bayer Chemicals AG (DE) | 2004-06-23 | — | — | EP | disclosed |