Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17984925 | 0.98 | HIF1A (0.41) | HIF1ATSHRTRPV1TRPA1FAAH | |
| SCHEMBL11902617 | 0.89 | TSHR (0.44) | HIF1ATSHRTRPV1TRPA1FAAH | |
| SCHEMBL4310324 | 0.83 | — | — | |
| SCHEMBL467527 | 0.83 | — | — | |
| SCHEMBL11067254 | 0.83 | — | — | |
| SCHEMBL7154944 | 0.83 | — | — | |
| SCHEMBL489139 | 0.83 | — | — | |
| SCHEMBL746873 | 0.78 | — | — | |
| SCHEMBL457172 | 0.78 | — | — | |
| SCHEMBL6967351 | 0.77 | TSHR (0.50) | HIF1ATSHRTRPV1TRPA1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195510-B | Process for producing glucopyranosyl derivative and intermediate therefor | 宜昌东阳光长江药业股份有限公司 | 2022-12-23 | — | — | CN | disclosed |