Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25196780 | 0.83 | TSHR (0.67) | TSHRFAAHTRPV1LMNAMAPT | |
| SCHEMBL15505936 | 0.83 | TSHR (0.67) | TSHRFAAHTRPV1LMNAMAPT | |
| SCHEMBL2635077 | 0.82 | TSHR (0.50) | TSHRALDH1A1FAAHTRPV1HIF1A | |
| SCHEMBL3459186 | 0.80 | TSHR (0.48) | TSHRALDH1A1FAAHTRPV1HIF1A | |
| SCHEMBL28389299 | 0.79 | TSHR (0.48) | TSHRALDH1A1FAAHTRPV1HIF1A | |
| SCHEMBL17984925 | 0.79 | HIF1A (0.41) | TSHRALDH1A1FAAHTRPV1HIF1A | |
| SCHEMBL17984936 | 0.79 | HIF1A (0.41) | TSHRHIF1ALMNA | |
| SCHEMBL13978053 | 0.78 | TSHR (0.54) | TSHRFAAHTRPV1LMNAMAPT | |
| SCHEMBL14237875 | 0.77 | TSHR (0.56) | TSHRALDH1A1FAAHTRPV1HIF1A | |
| Iodide SCHEMBL30151177 | 0.77 | HIF1A (0.39) | TSHRALDH1A1FAAHTRPV1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1285086-A2 | METHOD FOR DETECTING A DETECTABLE PRODUCT | Proteus (FR) | 2003-02-26 | — | — | EP | disclosed |
| WO-2001092563-A2 | METHOD FOR DETECTING A DETECTABLE PRODUCT | PROTEUS (FR) | 2001-12-06 | — | — | WO | disclosed |