Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | HTT | P42858 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 4/20 | 0.58 |
| ▸ | XBP1 | P17861 | 4/20 | 0.58 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.58 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.58 |
| ▸ | TERT | O14746 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30899614 | 1.00 | MAPT (0.58) | MAPTRAB9ANPC1HTTPOLB | |
| SCHEMBL6423690 | 1.00 | MAPT (0.58) | MAPTRAB9ANPC1HTTPOLB | |
| SCHEMBL30555815 | 0.83 | MAPT (0.64) | MAPTRAB9ANPC1HTTPOLB | |
| SCHEMBL27014677 | 0.81 | MAPT (0.51) | MAPTRAB9ANPC1HTTPOLB | |
| SCHEMBL25363305 | 0.81 | MAPT (0.51) | MAPTRAB9ANPC1HTTPOLB | |
| Brevilin A SCHEMBL27014670 | 0.80 | MAPT (0.52) | MAPTRAB9ANPC1HTTPOLB | |
| SCHEMBL27014666 | 0.80 | MAPT (0.55) | MAPTRAB9ANPC1HTTPOLB | |
| Brevilin A SCHEMBL27014668 | 0.80 | MAPT (0.52) | MAPTRAB9ANPC1HTTPOLB | |
| SCHEMBL9975665 | 0.78 | MAPT (0.48) | MAPTRAB9ANPC1HTTPOLB | |
| SCHEMBL27014729 | 0.78 | MAPT (0.51) | MAPTRAB9ANPC1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024123165-A1 | OPHTHALMIC FORMULATION FOR TOPICAL USE CONTAINING HELENALIN, 11Α,13-DIHYDRO HELENALIN AND FLAVONOIDS FROM ARNICA MONTANA EXTRACT AND SODIUM HYALURONATE, AND USE THEREOF BY HUMANS TO TREAT DRY EYE SYNDROME | CENTRO DE RETINA MÉDICA Y QUIRÚRGICA, S.C. (MX) | 2024-06-13 | — | — | WO | disclosed |
| US-20220409518-A1 | EMU Oil In Combination With Other Active Ingredients For Treating Skin Imperfections | DESAI, KETAN | 2022-12-29 | — | — | US | disclosed |