Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | HTT | P42858 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 4/20 | 0.58 |
| ▸ | XBP1 | P17861 | 4/20 | 0.58 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.58 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.58 |
| ▸ | TERT | O14746 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30899614 | 1.00 | MAPT (0.58) | MAPTRAB9ANPC1HTTPOLB | |
| SCHEMBL30151485 | 1.00 | MAPT (0.58) | MAPTRAB9ANPC1HTTPOLB | |
| SCHEMBL30555815 | 0.83 | MAPT (0.64) | MAPTRAB9ANPC1HTTPOLB | |
| SCHEMBL27014677 | 0.81 | MAPT (0.51) | MAPTRAB9ANPC1HTTPOLB | |
| SCHEMBL25363305 | 0.81 | MAPT (0.51) | MAPTRAB9ANPC1HTTPOLB | |
| Brevilin A SCHEMBL27014670 | 0.80 | MAPT (0.52) | MAPTRAB9ANPC1HTTPOLB | |
| SCHEMBL27014666 | 0.80 | MAPT (0.55) | MAPTRAB9ANPC1HTTPOLB | |
| Brevilin A SCHEMBL27014668 | 0.80 | MAPT (0.52) | MAPTRAB9ANPC1HTTPOLB | |
| SCHEMBL9975665 | 0.78 | MAPT (0.48) | MAPTRAB9ANPC1HTTPOLB | |
| SCHEMBL27014729 | 0.78 | MAPT (0.51) | MAPTRAB9ANPC1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998038971-A1 | THERAPEUTIC COMPOSITION AND METHOD FOR TREATING SKIN USING CENTIPEDA CUNNINGHAMI EXTRACT | BIO-BOTANICA, INC. (US) | 1998-09-11 | — | — | WO | claimed |
| US-5804206-A | PROVIDING PLANT MATERIAL OF CENTIPEDA GENUS IN POWDER FORM, SEQUENTIALLY MACERATING AND EXTRACTING WITH PLURALITY OF AQUEOUS/ETHANOLIC SOLVENTS OF DIFFERENT CONCENTRATION, COMBINING SOLUTIONS | BIO-BOTANICA, INC. (US) | 1998-09-08 | — | — | US | claimed |
| CN-108743583-A | Application of the sesquiterpene lactone chemical combination object in preparing the drug with antivirus action in Centipeda minima | 暨南大学 | 2018-11-06 | — | — | CN | disclosed |
| CN-104771393-B | Application of sesquiterpene lactone compounds in preparation of anti-influenza virus drugs | 暨南大学 | 2017-06-23 | — | — | CN | disclosed |
| CN-104771393-A | Application of sesquiterpene lactone compounds in preparation of anti-influenza virus drugs | UNIV JINAN | 2015-07-15 | — | — | CN | disclosed |
| EP-1509181-A1 | PERSONAL CARE ARTICLE AND METHOD FOR INHIBITING ATTACHMENT OF YEAST TO SKIN | Kimberly-Clark Worldwide, Inc. (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2004112819-A1 | COMPOSITIONS AND METHODS OF TREATMENT COMPRISING PLANT EXTRACTS | GELSTAT CORPORATION (US) | 2004-12-29 | — | — | WO | disclosed |
| WO-2003101356-A1 | PERSONAL CARE ARTICLE AND METHOD FOR INHIBITING ATTACHMENT OF YEAST TO SKIN | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2003-12-11 | — | — | WO | disclosed |
| US-20030224034-A1 | Personal care article and method for inhibiting attachment of yeast to skin | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-12-04 | — | — | US | disclosed |
| WO-1998038971-A1 | THERAPEUTIC COMPOSITION AND METHOD FOR TREATING SKIN USING CENTIPEDA CUNNINGHAMI EXTRACT | BIO-BOTANICA, INC. (US) | 1998-09-11 | — | — | WO | disclosed |
| US-5804206-A | PROVIDING PLANT MATERIAL OF CENTIPEDA GENUS IN POWDER FORM, SEQUENTIALLY MACERATING AND EXTRACTING WITH PLURALITY OF AQUEOUS/ETHANOLIC SOLVENTS OF DIFFERENT CONCENTRATION, COMBINING SOLUTIONS | BIO-BOTANICA, INC. (US) | 1998-09-08 | — | — | US | disclosed |
| US-5663196-A | ADMINISTERING A SESQUITERPENE LACTONE TO AN ANIMAL | BOSTON UNIVERSITY (US) | 1997-09-02 | — | — | US | disclosed |
| WO-1995006476-A1 | METHODS AND COMPOSITIONS FOR TREATING NEOPLASTIC DISORDERS | TRUSTEES OF BOSTON UNIVERSITY (US) | 1995-03-09 | — | — | WO | disclosed |