SCHEMBL30152143

SCHEMBL30152143

N[C@H](Cc1ccc(F)cc1Cl)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 0.51
▸ KDM4E B2RXH2 3/20 0.51
▸ CYP3A4 P08684 2/20 0.51
▸ CYP2C9 P11712 2/20 0.51
▸ MEN1 O00255 2/20 0.51
▸ ALDH1A1 P00352 2/20 0.51
▸ MAPT P10636 2/20 0.51
▸ HPGD P15428 2/20 0.51
▸ KMT2A Q03164 2/20 0.51
▸ PKM P14618 2/20 0.51
▸ ALOX15 P16050 2/20 0.51
▸ HIF1A Q16665 2/20 0.51
▸ HSD17B10 Q99714 2/20 0.51
▸ RECQL P46063 2/20 0.51
▸ TDP1 Q9NUW8 2/20 0.51
▸ RGS12 O14924 1/20 0.51
▸ NFKB1 P19838 1/20 0.51
▸ CASP1 P29466 1/20 0.51
▸ BRCA1 P38398 1/20 0.51
▸ THPO P40225 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30231991 1.00 USP2 (0.51) USP2KDM4ECYP3A4CYP2C9MEN1
SCHEMBL8007440 0.87 USP2 (0.51) USP2KDM4ECYP3A4CYP2C9MEN1
SCHEMBL44972 0.83 USP2 (0.54) USP2KDM4ECYP3A4CYP2C9MEN1
SCHEMBL10584810 0.83 USP2 (0.54) USP2KDM4ECYP3A4CYP2C9MEN1
SCHEMBL44973 0.83 USP2 (0.54) USP2KDM4ECYP3A4CYP2C9MEN1
SCHEMBL29414373 0.83 USP2 (0.54) USP2KDM4ECYP3A4CYP2C9MEN1
SCHEMBL44905 0.83 HDAC8 (0.58) USP2KDM4ECYP3A4CYP2C9MEN1
SCHEMBL29350881 0.83 HDAC8 (0.58) USP2KDM4ECYP3A4CYP2C9MEN1
SCHEMBL1613174 0.83 HDAC8 (0.58) USP2KDM4ECYP3A4CYP2C9MEN1
SCHEMBL44904 0.83 HDAC8 (0.58) USP2KDM4ECYP3A4CYP2C9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230040236-A1 Diamine-Linked Melanocortin Receptor-Specific Cyclic Peptides for Ocular Indications PALATIN TECHNOLOGIES, INC. (US) 2023-02-09 — — US disclosed
CN-115515617-A Diamine-linked receptor-specific cyclic peptides 帕拉丁科技公司 2022-12-23 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230040236-A1 Diamine-Linked Melanocortin Receptor-Specific Cyclic Peptides for Ocular Indications MC1R, MC3R, MC5R USP2 4019/4885KDM4E 4794/4885CYP3A4 4883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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