Sugi Predict

Sugi Predict / Compounds / SCHEMBL44973

SCHEMBL44973

SCHEMBL44973

N[C@@H](Cc1ccc(F)cc1F)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 0.54
▸ PKM P14618 2/20 0.54
▸ ALOX15 P16050 2/20 0.54
▸ HIF1A Q16665 2/20 0.54
▸ HSD17B10 Q99714 2/20 0.54
▸ KDM4E B2RXH2 2/20 0.54
▸ RECQL P46063 2/20 0.54
▸ TDP1 Q9NUW8 2/20 0.54
▸ RGS12 O14924 1/20 0.54
▸ CYP3A4 P08684 1/20 0.54
▸ CYP2C9 P11712 1/20 0.54
▸ NFKB1 P19838 1/20 0.54
▸ CASP1 P29466 1/20 0.54
▸ BRCA1 P38398 1/20 0.54
▸ THPO P40225 1/20 0.54
▸ CASP7 P55210 1/20 0.54
▸ GNAI1 P63096 1/20 0.54
▸ MEN1 O00255 1/20 0.54
▸ ALDH1A1 P00352 1/20 0.54
▸ LMNA P02545 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10584810 1.00 USP2 (0.54) USP2PKMALOX15HIF1AHSD17B10
SCHEMBL29414373 1.00 USP2 (0.54) USP2PKMALOX15HIF1AHSD17B10
SCHEMBL44972 1.00 USP2 (0.54) USP2PKMALOX15HIF1AHSD17B10
SCHEMBL29430355 0.86 USP2 (0.54) USP2PKMALOX15HIF1AHSD17B10
SCHEMBL188143 0.86 USP2 (0.54) USP2PKMALOX15HIF1AHSD17B10
SCHEMBL188142 0.86 USP2 (0.54) USP2PKMALOX15HIF1AHSD17B10
SCHEMBL14271135 0.85 DPP4 (0.48) DPP4DPP7FAPDPP8DPP9
SCHEMBL751609 0.85 USP2 (0.57) USP2PKMALOX15HIF1AHSD17B10
SCHEMBL1577675 0.85 USP2 (0.57) USP2PKMALOX15HIF1AHSD17B10
SCHEMBL12375142 0.85 USP2 (0.57) USP2PKMALOX15HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 891 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612605-B2 Carboxyesterase polypeptides for kinetic resolution CODEXIS, INC. (US) 2026-04-28 — — US disclosed
US-20260078417-A1 TRANSAMINASE BIOCATALYSTS CODEXIS, INC. (US) 2026-03-19 — — US disclosed
US-12565641-B2 Engineered terminal deoxynucleotidyl transferase variants CODEXIS, INC. (US) 2026-03-03 — — US disclosed
US-12565517-B2 Cyclic peptide having CTLA-4 inhibitory activity and use thereof GENEFRONTIER CORPORATION (JP) 2026-03-03 — — US disclosed
US-20260043010-A1 ENONE REDUCTASES CODEXIS, INC. (US) 2026-02-12 — — US disclosed
EP-4687443-A1 METHOD FOR FUNCTIONALISING A SOLID SUBSTRATE WITH A PEPTIDE CONJUGATE Genepep (FR) 2026-02-11 — — EP disclosed
US-20260028600-A1 TRANSAMINASE POLYPEPTIDES CODEXIS INC (US) 2026-01-29 — — US disclosed
US-20260022366-A1 ENGINEERED NITROALDOLASES CODEXIS INC (US) 2026-01-22 — — US disclosed
WO-2025264722-A1 ENGINEERED 3'O-KINASE VARIANTS CODEXIS, INC. (US) 2025-12-26 — — WO disclosed
WO-2025264715-A1 ENGINEERED PYRUVATE OXIDASE VARIANTS 0/CODEXIS, INC. (US) 2025-12-26 — — WO disclosed
US-20030170738-A1 Compounds that modulate processes associated with IgE production and methods and kits for identifying and using the same RIGEL PHARMACEUTICALS, INC. 2003-09-11 — — US disclosed
US-20030166138-A1 Cyclic peptides and analogs useful to treat allergies RIGEL PHARMACEUTICALS, INC. 2003-09-04 — — US disclosed
WO-2003072034-A2 CYCLIC PEPTIDES AND ANALOGS USEFUL TO TREAT ALLERGIES RIGEL PHARMACEUTICALS, INC. (US) 2003-09-04 — — WO disclosed
EP-0720601-A1 GASTRIN AND CCK RECEPTOR LIGANDS JAMES BLACK FOUNDATION LIMITED (GB) 1996-07-10 — — EP disclosed
WO-1995004720-A2 GASTRIN AND CCK RECEPTOR LIGANDS BLACK JAMES FOUNDATION (GB) 1995-02-16 — — WO disclosed
EP-0310948-A2 Process for the preparation of optically pure phenyl ring-substituted phenyl alamine derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-12 — — EP disclosed
US-4766110-A INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS RYAN JAMES W (US) 1988-08-23 — — US disclosed
EP-0073143-B1 NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES Ryan, James Walter (US) 1985-11-21 — — EP disclosed
EP-0073143-A2 Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides Ryan, James Walter (US) 1983-03-02 — — EP disclosed
EP-0048159-A2 Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents UNIVERSITY OF MIAMI (US) 1982-03-24 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022366-A1 ENGINEERED NITROALDOLASES NOS2, NOS1, NOS3 USP2 1120/4885PKM 1070/4885ALOX15 2815/4885
US-12565517-B2 Cyclic peptide having CTLA-4 inhibitory activity and use thereof CXCL10, MLX, MICA USP2 4057/4885PKM 3268/4885ALOX15 4783/4885
US-12565641-B2 Engineered terminal deoxynucleotidyl transferase variants DNTT, RNGTT, POLM USP2 3062/4885PKM 4382/4885ALOX15 4806/4885
US-12612605-B2 Carboxyesterase polypeptides for kinetic resolution CES1, CPA1, RNGTT USP2 178/4885PKM 2702/4885ALOX15 2988/4885
US-20260043010-A1 ENONE REDUCTASES DCXR, ENY2, UPF1 USP2 1757/4885PKM 1448/4885ALOX15 3572/4885
US-20260028600-A1 TRANSAMINASE POLYPEPTIDES GOT1, OAT, PEPD USP2 1874/4885PKM 20/4885ALOX15 4256/4885
US-20260078417-A1 TRANSAMINASE BIOCATALYSTS XDH, AGXT, PEPD USP2 1031/4885PKM 392/4885ALOX15 3792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.