Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | GUSB | P08236 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 9/20 | 0.53 |
| ▸ | MAOA | P21397 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29690244 | 1.00 | RECQL (0.59) | RECQLMAPTKMT2AMAPK1TDP1 | |
| SCHEMBL6769396 | 1.00 | RECQL (0.59) | RECQLMAPTKMT2AMAPK1TDP1 | |
| SCHEMBL6769397 | 1.00 | RECQL (0.59) | RECQLMAPTKMT2AMAPK1TDP1 | |
| SCHEMBL12315710 | 0.81 | RECQL (0.59) | RECQLMAPTKMT2ATDP1MEN1 | |
| SCHEMBL29750390 | 0.81 | RECQL (0.59) | RECQLMAPTKMT2ATDP1MEN1 | |
| SCHEMBL3742734 | 0.81 | RECQL (0.59) | RECQLMAPTKMT2ATDP1MEN1 | |
| SCHEMBL29176318 | 0.81 | RECQL (0.59) | RECQLMAPTKMT2ATDP1MEN1 | |
| SCHEMBL13978671 | 0.81 | MAPT (0.51) | MAPTKMT2AMAPK1TDP1MEN1 | |
| SCHEMBL2210433 | 0.80 | TDP1 (0.67) | RECQLMAPTMAPK1TDP1NPC1 | |
| SCHEMBL7136836 | 0.80 | RECQL (0.58) | RECQLMAPTKMT2ATDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514758-B | Chromone derivative and synthesis method thereof | 南京工业大学 | 2024-12-24 | — | — | CN | disclosed |
| CN-118221690-A | Chromone pyridazine compound and synthetic method and application thereof | 昆明理工大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-118005593-A | Preparation method of 2, 3-disubstituted chromone compound | 昆明理工大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-116514758-A | Chromone derivative and synthesis method thereof | 南京工业大学 | 2023-08-01 | — | — | CN | disclosed |
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |