Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | GUSB | P08236 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 9/20 | 0.53 |
| ▸ | MAOA | P21397 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152192 | 1.00 | RECQL (0.59) | RECQLMAPTKMT2AMAPK1TDP1 | |
| SCHEMBL29690244 | 1.00 | RECQL (0.59) | RECQLMAPTKMT2AMAPK1TDP1 | |
| SCHEMBL6769397 | 1.00 | RECQL (0.59) | RECQLMAPTKMT2AMAPK1TDP1 | |
| SCHEMBL12315710 | 0.81 | RECQL (0.59) | RECQLMAPTKMT2ATDP1MEN1 | |
| SCHEMBL29750390 | 0.81 | RECQL (0.59) | RECQLMAPTKMT2ATDP1MEN1 | |
| SCHEMBL3742734 | 0.81 | RECQL (0.59) | RECQLMAPTKMT2ATDP1MEN1 | |
| SCHEMBL29176318 | 0.81 | RECQL (0.59) | RECQLMAPTKMT2ATDP1MEN1 | |
| SCHEMBL13978671 | 0.81 | MAPT (0.51) | MAPTKMT2AMAPK1TDP1MEN1 | |
| SCHEMBL2210433 | 0.80 | TDP1 (0.67) | RECQLMAPTMAPK1TDP1NPC1 | |
| SCHEMBL7136836 | 0.80 | RECQL (0.58) | RECQLMAPTKMT2ATDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624044-B2 | SMARCA degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2026-05-12 | — | — | US | disclosed |
| CN-118221690-A | Chromone pyridazine compound and synthetic method and application thereof | 昆明理工大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-118005593-A | Preparation method of 2, 3-disubstituted chromone compound | 昆明理工大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-116514758-A | Chromone derivative and synthesis method thereof | 南京工业大学 | 2023-08-01 | — | — | CN | disclosed |
| US-20230115350-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. | 2023-04-13 | — | — | US | disclosed |
| US-20230072658-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-03-09 | — | — | US | disclosed |
| US-20230072658-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-03-09 | — | — | US | disclosed |
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |
| US-20210293825-A1 | METHODS FOR PRECISION THERAPEUTIC TARGETING OF HUMAN CANCER CELL MOTILITY AND KITS THEREOF | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2021-09-23 | — | — | US | disclosed |
| US-20210293825-A1 | METHODS FOR PRECISION THERAPEUTIC TARGETING OF HUMAN CANCER CELL MOTILITY AND KITS THEREOF | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2021-09-23 | — | — | US | disclosed |
| US-20160128973-A1 | INHIBITION OF CANCER CELL MOTILITY | NORTHWESTERN UNIVERSITY | 2016-05-12 | — | — | US | disclosed |
| WO-2015114102-A1 | SILYL SUBSTITUTED AZADIBENZOFURANS AND AZADIBENZOTHIOPHENES | BASF SE (DE) | 2015-08-06 | — | — | WO | disclosed |
| WO-2015114102-A1 | SILYL SUBSTITUTED AZADIBENZOFURANS AND AZADIBENZOTHIOPHENES | BASF SE (DE) | 2015-08-06 | — | — | WO | disclosed |
| US-8772293-B2 | Chemical compounds | PFIZER LIMITED (GB) | 2014-07-08 | — | — | US | disclosed |
| US-20120010182-A1 | Chemical Compounds | ICAGEN INC. (US) | 2012-01-12 | — | — | US | disclosed |
| US-20040242633-A1 | Beta3 adrenergic agonists | EVERS BRITTA (DE) | 2004-12-02 | — | — | US | disclosed |
| US-6730792-B2 | PYRIDINE DERIVATIVES; ANTIDIABETIC, ANTICHOLESTEROL, AND ANTIINFLAMMATORY AGENTS; DECYCLIZATION, DEETHERIFICATION; OBESITY; RAISES HIGH DENSITY LIPOPROTEINS; LOWERS TRIGLYCERIDE LEVELS | ELI LILLY AND COMPANY | 2004-05-04 | — | — | US | disclosed |
| US-20030191156-A1 | Beta3 adrenergic agonists | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR COLLATERAL AGENT | 2003-10-09 | — | — | US | disclosed |
| EP-1303509-A1 | BETA3 ADRENERGIC AGONISTS | ELI LILLY AND COMPANY (US) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002006276-A1 | BETA3 ADRENERGIC AGONISTS | ELI LILLY AND COMPANY (US) | 2002-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230115350-A1 | TEAD INHIBITORS AND USES THEREOF | TEAD2, TEAD3, TEAD4 | RECQL 389/4885MAPT 506/4885KMT2A 3787/4885 |
| US-20030191156-A1 | Beta3 adrenergic agonists | ADRB3, ADRB1, ADRB2 | RECQL 4054/4885MAPT 1813/4885KMT2A 3262/4885 |
| US-20040242633-A1 | Beta3 adrenergic agonists | ADRB3, ADRB1, ADRB2 | RECQL 3997/4885MAPT 2096/4885KMT2A 3460/4885 |
| US-20160128973-A1 | INHIBITION OF CANCER CELL MOTILITY | MMP26, MKI67, EPCAM | RECQL 4129/4885MAPT 3601/4885KMT2A 1883/4885 |
| US-20120010182-A1 | Chemical Compounds | SCN1A, SCN1B, CACNA1E | RECQL 1341/4885MAPT 3814/4885KMT2A 2068/4885 |
| US-12624044-B2 | SMARCA degraders and uses thereof | SMARCA1, SMARCC1, SMARCA2 | RECQL 882/4885MAPT 2169/4885KMT2A 212/4885 |
| US-20230072658-A1 | SMARCA DEGRADERS AND USES THEREOF | SMARCA1, SMARCB1, SMARCE1 | RECQL 793/4885MAPT 1445/4885KMT2A 380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.