Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 8/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24969071 | 1.00 | NISCH (0.43) | NISCHROCK2NPC1LMNARAB9A | |
| SCHEMBL30702607 | 0.82 | NISCH (0.49) | NISCHROCK2 | |
| SCHEMBL30615439 | 0.75 | NISCH (0.46) | NISCHROCK2HDAC1HDAC2MAOB | |
| SCHEMBL30152308 | 0.75 | PLAU (0.42) | NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL24968850 | 0.75 | PLAU (0.42) | NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL24969521 | 0.74 | MAPT (0.43) | NISCHNPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL24969062 | 0.73 | MAOB (0.44) | ROCK2HDAC1HDAC2MAOB | |
| SCHEMBL30152292 | 0.73 | MAOB (0.44) | ROCK2HDAC1HDAC2MAOB | |
| SCHEMBL6204486 | 0.72 | CYP19A1 (0.51) | NISCHROCK2 | |
| SCHEMBL24969069 | 0.71 | CYP3A4 (0.48) | NISCHNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |