Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968850 | 1.00 | PLAU (0.42) | PLAUPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30084892 | 0.76 | CHRNB2 (0.41) | MAPTALDH1A1LMNAMAPK1GFER | |
| SCHEMBL13014935 | 0.76 | CHRNB2 (0.41) | MAPTALDH1A1LMNAMAPK1GFER | |
| SCHEMBL24969071 | 0.75 | NISCH (0.43) | LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30152236 | 0.75 | NISCH (0.43) | LMNANPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL287323 | 0.75 | CHRNB2 (0.40) | MAPTALDH1A1LMNAMAPK1GFER | |
| SCHEMBL12474593 | 0.74 | CRBN (0.40) | — | |
| SCHEMBL21988069 | 0.73 | ALOX5AP (0.40) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26131159 | 0.73 | OPRL1 (0.41) | MAPTALDH1A1GFERKDM4ENPC1 | |
| SCHEMBL240676 | 0.72 | NUDT1 (0.42) | MAPTALDH1A1GFERKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |