Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1406632 | 1.00 | HTR1A (0.55) | HTR1AADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL1406869 | 0.86 | MRGPRX4 (0.54) | HTR1AADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL30152254 | 0.86 | MEN1 (0.51) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL3366592 | 0.86 | MEN1 (0.51) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL1578513 | 0.86 | CYP19A1 (0.63) | HTR1AADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL30354869 | 0.85 | MAPT (0.67) | HTR1AADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL5929724 | 0.85 | MAPT (0.67) | HTR1AADRA1DADRA1AADRA1BMEN1 | |
| SCHEMBL141880 | 0.84 | EGFR (0.59) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4031443 | 0.84 | MEN1 (0.49) | MEN1KMT2AMAPTALDH1A1CYP19A1 | |
| SCHEMBL30152359 | 0.84 | MAPT (0.49) | MEN1KMT2AMAPTCYP19A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |