Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 6/20 | 0.42 |
| ▸ | EGFR | P00533 | 8/20 | 0.40 |
| ▸ | ITK | Q08881 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.38 |
| ▸ | TGM1 | P22735 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968851 | 1.00 | TGM2 (0.42) | TGM2EGFRITKKMT2AF13A1 | |
| SCHEMBL24969062 | 0.81 | MAOB (0.44) | TGM2EGFRITK | |
| SCHEMBL30152292 | 0.81 | MAOB (0.44) | TGM2EGFRITK | |
| SCHEMBL28996912 | 0.75 | TGM2 (0.42) | TGM2EGFRITKF13A1TGM1 | |
| SCHEMBL29369451 | 0.75 | TGM2 (0.42) | TGM2EGFRITKF13A1TGM1 | |
| SCHEMBL28997055 | 0.75 | TGM2 (0.39) | TGM2EGFRITKF13A1TGM1 | |
| SCHEMBL26123112 | 0.73 | TGM2 (0.42) | TGM2EGFRITKF13A1TGM1 | |
| SCHEMBL29369857 | 0.73 | TGM2 (0.42) | TGM2EGFRITKF13A1TGM1 | |
| SCHEMBL28996930 | 0.72 | TGM2 (0.54) | TGM2EGFRITKKMT2AF13A1 | |
| SCHEMBL29370301 | 0.72 | TGM2 (0.54) | TGM2EGFRITKKMT2AF13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |