Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24969547 | 1.00 | KDM5A (0.35) | KDM5AKDM4CKDM5BMCHR1LRRK2 | |
| SCHEMBL24969545 | 0.85 | KDM5A (0.35) | KDM5AKDM4CKDM5BLRRK2SCN9A | |
| SCHEMBL30152345 | 0.85 | KDM5A (0.35) | KDM5AKDM4CKDM5BLRRK2SCN9A | |
| SCHEMBL24968804 | 0.77 | CDK2 (0.42) | KDM5AKDM4CKDM5BMCHR1LRRK2 | |
| SCHEMBL30152341 | 0.77 | CDK2 (0.42) | KDM5AKDM4CKDM5BMCHR1LRRK2 | |
| SCHEMBL24969039 | 0.76 | MAPK3 (0.38) | KDM5AKDM4CKDM5BSCN9ASCN5A | |
| SCHEMBL30152334 | 0.76 | MAPK3 (0.38) | KDM5AKDM4CKDM5BSCN9ASCN5A | |
| SCHEMBL30152244 | 0.74 | SCN9A (0.35) | KDM5AKDM4CKDM5BLRRK2SCN9A | |
| SCHEMBL24969549 | 0.74 | SCN9A (0.35) | KDM5AKDM4CKDM5BLRRK2SCN9A | |
| SCHEMBL20554482 | 0.73 | HSP90AA1 (0.40) | KDM5AKDM4CKDM5BMCHR1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |