Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 8/20 | 0.42 |
| ▸ | CDK1 | P06493 | 7/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 5/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968804 | 1.00 | CDK2 (0.42) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL30152188 | 0.82 | CDK2 (0.33) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL30152322 | 0.79 | CDK2 (0.38) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL24968800 | 0.79 | CDK2 (0.38) | CDK2CDK1CCNB1CCNA2CCNA1 | |
| SCHEMBL24968801 | 0.77 | EGFR (0.38) | MAPK3SCN9ASCN5A | |
| SCHEMBL30152336 | 0.77 | EGFR (0.38) | MAPK3SCN9ASCN5A | |
| SCHEMBL24969547 | 0.77 | KDM5A (0.35) | MCHR1KDM5AKDM4CKDM5BSCN9A | |
| SCHEMBL30152285 | 0.77 | KDM5A (0.35) | MCHR1KDM5AKDM4CKDM5BSCN9A | |
| SCHEMBL20554482 | 0.74 | HSP90AA1 (0.40) | MCHR1KDM5AKDM4CKDM5BBRD4 | |
| SCHEMBL24968803 | 0.72 | MCHR1 (0.42) | MCHR1KDM5AKDM4CKDM5BSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |