Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.38 |
| ▸ | KDR | P35968 | 11/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 1/20 | 0.37 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968801 | 1.00 | EGFR (0.38) | EGFRKDRMAPK3CCNKCDK12 | |
| SCHEMBL30152334 | 0.81 | MAPK3 (0.38) | EGFRKDRMAPK3CCNKCDK12 | |
| SCHEMBL24969039 | 0.81 | MAPK3 (0.38) | EGFRKDRMAPK3CCNKCDK12 | |
| SCHEMBL24968530 | 0.79 | MAPK3 (0.43) | EGFRKDRMAPK3SCN9ASCN5A | |
| SCHEMBL20554317 | 0.79 | PDE4D (0.47) | EGFRKDRMAPK3BTK | |
| SCHEMBL24968499 | 0.77 | MAPK3 (0.40) | EGFRKDRMAPK3CCNKCDK12 | |
| SCHEMBL30152401 | 0.77 | MAPK3 (0.40) | EGFRKDRMAPK3CCNKCDK12 | |
| SCHEMBL24968804 | 0.77 | CDK2 (0.42) | MAPK3SCN9ASCN5A | |
| SCHEMBL30152341 | 0.77 | CDK2 (0.42) | MAPK3SCN9ASCN5A | |
| SCHEMBL24968810 | 0.75 | SCN9A (0.41) | EGFRCCNKCDK12SCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |