Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 2/20 | 0.42 |
| ▸ | VSIR | Q9H7M9 | 4/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24820272 | 1.00 | CBLB (0.42) | CBLBVSIRPDCD1CD274 | |
| SCHEMBL30152883 | 0.92 | CBLB (0.36) | CBLBVSIRPDCD1CD274 | |
| SCHEMBL30153132 | 0.92 | CBLB (0.36) | CBLBVSIRPDCD1CD274 | |
| SCHEMBL24820294 | 0.92 | CBLB (0.36) | CBLBVSIRPDCD1CD274 | |
| SCHEMBL24820588 | 0.92 | CBLB (0.36) | CBLBVSIRPDCD1CD274 | |
| SCHEMBL24818396 | 0.90 | CBLB (0.38) | CBLBVSIRPDCD1CD274 | |
| SCHEMBL30153064 | 0.90 | CBLB (0.38) | CBLBVSIRPDCD1CD274 | |
| SCHEMBL24819883 | 0.87 | VSIR (0.42) | CBLBVSIRPDCD1CD274 | |
| SCHEMBL24821930 | 0.87 | CBLB (0.39) | CBLB | |
| SCHEMBL24820589 | 0.87 | CBLB (0.33) | CBLBVSIRPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |